Survival factors regulating ovarian apoptosis--dependence on follicle differentiation

E Markstrom, EC Svensson, R Shao… - …, 2002 - rep.bioscientifica.com
Epigenetic reprogramming plays a pivotal role during embryogenesis, including both
covalent and non-covalent modifications to chromatin. In this study, we investigated the role …

Neuroblastoma treatment in the post-genomic era

MR Esposito, S Aveic, A Seydel, GP Tonini - Journal of biomedical science, 2017 - Springer
Neuroblastoma is an embryonic malignancy of early childhood originating from neural crest
cells and showing heterogeneous biological, morphological, genetic and clinical …

Resveratrol induces autophagy and apoptosis in non-small-cell lung cancer cells by activating the NGFR-AMPK-mTOR pathway

J Li, Y Fan, Y Zhang, Y Liu, Y Yu, M Ma - Nutrients, 2022 - mdpi.com
Resveratrol (RSV) has been reported to induce autophagy and apoptosis in non-small-cell
lung cancer A549 cells, and the nerve growth factor receptor (NGFR) regulates autophagy …

Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver

J Wang, D Mauvoisin, E Martin, F Atger, AN Galindo… - Cell metabolism, 2017 - cell.com
Diurnal oscillations of gene expression controlled by the circadian clock and its connected
feeding rhythm enable organisms to coordinate their physiologies with daily environmental …

Progress and promises of epigenetic drugs and epigenetic diets in cancer prevention and therapy: A clinical update

P Mondal, J Natesh, D Penta, SM Meeran - Seminars in Cancer Biology, 2022 - Elsevier
Epigenetic modifications are heritable yet reversible, essential for normal physiological
functions and biological development. Aberrant epigenetic modifications, including DNA …

[HTML][HTML] Targeting EZH2 in neuroblastoma

J Gao, C Fosbrook, J Gibson, TJ Underwood… - Cancer Treatment …, 2023 - Elsevier
Neuroblastoma is one of the commonest extra-cranial pediatric tumors, and accounts for
over 15% of all childhood cancer mortality. Risk stratification for children with neuroblastoma …

Modulation of multiple signaling pathways of the plant-derived natural products in cancer

L Sun, W Zhou, H Zhang, Q Guo, W Yang, B Li… - Frontiers in …, 2019 - frontiersin.org
Natural compounds are highly effective anticancer chemotherapeutic agents, and the targets
of plant-derived anticancer agents have been widely reported. In this review, we focus on …

Natural products modulating epigenetic mechanisms by affecting histone methylation/demethylation: Targeting cancer cells

D Dorna, A Grabowska… - British Journal of …, 2023 - Wiley Online Library
Many natural products can exert anticancer or chemopreventive activity by interfering with
the cellular epigenetic machinery. Many studies indicate the relevance of affecting DNA …

Involvement of microRNA modifications in anticancer effects of major polyphenols from green tea, coffee, wine, and curry

T Ohishi, S Hayakawa, N Miyoshi - Critical Reviews in Food …, 2023 - Taylor & Francis
Epidemiological studies have shown that consumption of green tea, coffee, wine, and curry
may contribute to a reduced risk of various cancers. However, there are some cancer site …

MicroRNAs: diverse mechanisms of action and their potential applications as cancer epi-therapeutics

A Sadakierska-Chudy - Biomolecules, 2020 - mdpi.com
Usually, miRNAs function post-transcriptionally, by base-pairing with the 3′ UTR of target
mRNAs, repressing protein synthesis in the cytoplasm. Furthermore, other regions including …