To the Editor: Plasmodium vivax is the protozoan that causes the second most common form
of malaria. Some resistant strains to chloroquine (CQ) occur in a few places in Asia and the …

Delineating its usage in separation, purification and detection processes across a variety of
disciplines, from industry to applied research, this work discusses the principles, techniques …

With the outbreak caused by the severe acute respiratory syndrome coronavirus (COVID-
19), people's health and existing economies on a global scale are seriously threatened …

Chloroquine (CQ)(1) which has endured as one of the most powerful antimalarial drugs was
subjected to oxidative stress conditions and the degradation profile was studied. The …

The development of new antimalarial drugs is urgent to overcome the spread of resistance
to the current treatment. Herein we synthesized the compound 3, a hit-to‑lead optimization of …

Objective: Drug quality may be poor in many regions of the world. Our first aim was to verify
whether the dose of the active compounds in various antimalarial medicines on the market …

A simple, sensitive and rapid liquid chromatography/tandem mass spectrometric (LC–
MS/MS) method was developed and validated for quantification of chloroquine, an …

A simple and rapid development of a stability-indicating LC method for determination of
chloroquine diphosphate in the presence of its hydrolysis, oxidative and photolysis …

Background: Quantification of polar compounds such as chloroquine by revered-phase LC
is a challenge because of poor retention and silanol interactions with stationary phase …

A dead body of middle aged man was exhumed from 6.5 month earth-grave. Autopsy
findings were non-specific as the body was completely putrefied. Deceased's scalp hair and …