Plant secondary metabolites (PSMs) play many roles including defense against pathogens,
pests, and herbivores; response to environmental stresses, and mediating organismal …

Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and
interpret the tsunami of metagenomic sequencing data generated by high-throughput …

Background Microbiome studies often involve sequencing a marker gene to identify the
microorganisms in samples of interest. Sequence classification is a critical component of this …

The epidermis forms a barrier that defends the body from desiccation and entry of harmful
substances, while also sensing and integrating environmental signals. The tightly …

Clustering homologous sequences based on their similarity is a problem that appears in
many bioinformatics applications. The fact that sequences cluster is ultimately the result of …

The effective use of metabarcoding in biodiversity science has brought important analytical
challenges due to the need to generate accurate taxonomic assignments. The assignment of …

Every year, 11% of infants are born preterm with significant health consequences, with the
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …

Background The low cost of 16S rRNA gene sequencing facilitates population-scale
molecular epidemiological studies. Existing computational algorithms can resolve 16S rRNA …

Skin is colonized by microbial communities (microbiota) that participate in immune
homeostasis, development and maintenance of barrier function, and protection from …

Phylogenetic placement of query samples on an existing phylogeny is increasingly used in
molecular ecology, including sample identification and microbiome environmental sampling …