Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions

JD Lasso, DJ Castillo-Pazos, CJ Li - Chemical Society Reviews, 2021 - pubs.rsc.org
The progress of drug discovery and development is paced by milestones reached in organic
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …

Cobalt ferrite nanoparticles (CoFe2O4 MNPs) as catalyst and support: magnetically recoverable nanocatalysts in organic synthesis

M Kazemi, M Ghobadi, A Mirzaie - Nanotechnology reviews, 2018 - degruyter.com
Recovery and reusability of catalysts is an important aspect in modern catalysis research
especially in organic synthesis. Compared to the conventional separation, magnetic …

Transition-metal-catalyzed denitrative coupling of nitroarenes

K Muto, T Okita, J Yamaguchi - ACS Catalysis, 2020 - ACS Publications
Functionalization of arenes is a topic of central importance in diverse fields ranging from
medicinal chemistry to materials science. Metal-catalyzed cross-coupling and nucleophilic …

Significantly improved method for the Pd-catalyzed coupling of phenols with aryl halides: understanding ligand effects

M Fioroni, NJ DeYonker - Angewandte …, 2006 - digitalcommons.memphis.edu
By means of quantum chemistry (PBE0/def2-TZVPP; DLPNO-CCSD (T)/cc-pVTZ) and small,
but reliable models of Polyhedral Oligomeric Silsesquioxanes (POSS), an array of …

A general and efficient catalyst for palladium-catalyzed C− O coupling reactions of aryl halides with primary alcohols

S Gowrisankar, AG Sergeev, P Anbarasan… - Journal of the …, 2010 - ACS Publications
An efficient procedure for palladium-catalyzed coupling reactions of (hetero) aryl bromides
and chlorides with primary aliphatic alcohols has been developed. Key to the success is the …

Hydrogen generation at ambient conditions: application in fuel cells

A Boddien, B Loges, H Junge… - … & Sustainability Energy & …, 2008 - Wiley Online Library
The efficient generation of hydrogen from formic acid/amine adducts at ambient temperature
is demonstrated. The highest catalytic activity (TOF up to 3630 h− 1 after 20 min) was …

Cu-catalyzed arylation of phenols: synthesis of sterically hindered and heteroaryl diaryl ethers

D Maiti, SL Buchwald - The Journal of organic chemistry, 2010 - ACS Publications
Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under
mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This …

Practical Imidazole‐Based Phosphine Ligands for Selective Palladium‐Catalyzed Hydroxylation of Aryl Halides.

T Schulz, C Torborg, B Schäffner, J Huang, A Zapf… - …, 2009 - Wiley Online Library
www.cheminform.wiley-vch.de Monovalent phenols Q 0180 Practical Imidazole-Based
Phosphine Ligands for Selective Palladium-Cataly Page 1 ChemInform 2009, 40, issue 22 © …

A Single Phosphine Ligand Allows Palladium‐Catalyzed Intermolecular C O Bond Formation with Secondary and Primary Alcohols

X Wu, BP Fors, SL Buchwald - … Chemie International Edition, 2011 - Wiley Online Library
Aryl alkyl ethers are present in many naturally occurring and medicinally relevant
compounds.[1] Copper [2]-and palladiumcatalyzed CÀO bond-forming reactions have …

Decarbonylative diaryl ether synthesis by Pd and Ni catalysis

R Takise, R Isshiki, K Muto, K Itami… - Journal of the American …, 2017 - ACS Publications
Because diaryl ethers are present as an important motif in pharmaceuticals and natural
products, extensive studies for the development of novel methods have been conducted. A …