Current epidemiological data estimate that one in five people suffers from chronic pain with
considerable impairment of health-related quality of life. The pharmacological treatment is …

In this review, the latest insights into habituation to pain in chronic pain are summarized.
Using a systematic search, results of studies on the evidence of habituation to …

Pain is the most frequent symptom of disease. In treating pain, a lower incidence of adverse
effects is found for paracetamol versus other non-steroidal anti-inflammatory drugs …

Abstract Chronic Overlapping Pain Conditions (COPCs) are a subset of chronic pain
conditions commonly comorbid with one another and more prevalent in women and …

Accumulating evidence supports the notion that microglia play versatile roles in different
chronic pain conditions. However, therapeutic strategies of chronic pain by targeting …

Diabetic neuropathy (DN) is a neurodegenerative disorder that is primarily characterized by
distal sensory loss, reduced mobility, and foot ulcers that may potentially lead to amputation …

Pain is a complex and multifaceted experience. Recent research has increasingly focused
on the role of endoplasmic reticulum (ER) stress in the induction and modulation of pain …

目的三叉神经痛(trigeminal neuralgia， TN) 是一种严重的慢性神经病理性疼痛，
主要影响三叉神经分布区域， 临床治疗效果不佳。 TN 的治疗方法众多， 但目前临床上主要是 …

Introduction: Drug treatment can be related to the development of adverse drug reactions
(ADRs). Aim: In this paper, we evaluated ADRs in patients admitted to the Ambulatory of …

Pain embodies a complex sensory experience influenced by a medley of biological,
psychological, and genetic. Pain perception can be classed into four main categories …