Obesity rates are increasing worldwide and there is a need for novel therapeutic treatment
options. The endocannabinoid system has been linked to homeostatic processes, including …

A series of fifteen novel isatin oxime ether-tethered aryl 1H-1, 2, 3-triazole hybrids 5a–o
were designed and synthesized by employing Cu (I) catalyzed azide–alkyne [3+ 2] …

The two subtypes of cannabinoid receptors (CBR), namely CB 1 R and CB 2 R, belong to
the G protein-coupled receptor (GPCR) superfamily and are confirmed as potential …

A series of eight novel ferrocene–oxime ether benzyl 1H-1, 2, 3 triazole hybrids 5a–h were
designed and synthesized by employing Cu (I) catalyzed azide–alkyne [3+ 2] cycloaddition …

The cobalt‐catalyzed reaction between 1, 3‐dithiolanes and Grignard reagents, for the
efficient synthesis of multi‐substituted alkene products, is described. The method was …

In earlier work, we explored the SAR for the C3 side chain pharmacophore in the
hexahydrocannabinol template represented by the drug nabilone, which resulted in the …

Preparations of Cannabis sativa have been used in traditional medicine to treat various
conditions, such as pain, inflammation, and epilepsy, and for recreational purposes across …

The Cannabinoid (CB) signalling cascade is widely located in the human body and is
associated with several pathophysiological processes. The endocannabinoid system …

Background and Purpose Δ9‐tetrahydrocannabinol (THC) acts via cannabinoid CB1
receptors to increase feeding. Here, we assessed the orexigenic effect of AM11101, a novel …

The fatty acid amide hydrolase (FAAH, EC 3.5. 1.99) is an integral intracellular membrane-
bound enzyme that was properly characterized in the mid-1980s, 1 although an N …