The tooth root is an integral, functionally important part of our dentition. The formation of a
functional root depends on epithelial-mesenchymal interactions and integration of the root …

BMP signaling plays an important role in dentin development. BMPs and antagonists
regulate odontoblast differentiation and downstream gene expression via canonical Smad …

Now entering its 40th anniversary, the fifth edition of Oral Anatomy, Histology and
Embryology has been thoroughly overhauled, updated and augmented to meet the needs of …

Experimental studies have shown a great potential for periodontal regeneration. The
limitations of periodontal regeneration largely depend on the regenerative potential at the …

It is known that stem cells from exfoliated deciduous teeth (SHED) can be induced to
differentiate into odontoblasts. However, the nature of dentin-derived morphogenic signals …

Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the
Drosophila muscle segment homeobox gene. These genes are expressed at multiple sites …

Most characteristics of tooth shape and pattern can be altered by modulating the signal
pathways mediating epithelial–mesenchymal interactions in developing teeth. These …

The dental follicle (DF) surrounding the developing tooth germ is an ectomesenchymal
tissue composed of various cell populations derived from the cranial neural crest. Human …

Dental pulp has intrinsic capacity for self-repair. However, it is not clear whether dental pulp
cells can be recruited endogenously for regenerating pulp tissues, including mineralizing …

There is evidence in Xenopus and zebrafish embryos that the neural crest/neural folds are
specified at the border of the neural plate by a precise threshold concentration of a Bmp …