Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
Exosomes: extracellular organelles important in intercellular communication
In addition to intracellular organelles, eukaryotic cells also contain extracellular organelles
that are released, or shed, into the microenvironment. These membranous extracellular …
that are released, or shed, into the microenvironment. These membranous extracellular …
Exosomes: proteomic insights and diagnostic potential
Exosomes are 40–100-nm diameter membrane vesicles of endocytic origin that are
released by most cell types upon fusion of multivesicular bodies with the plasma membrane …
released by most cell types upon fusion of multivesicular bodies with the plasma membrane …
Harnessing 64Cu/67Cu for a theranostic approach to pretargeted radioimmunotherapy
O Keinänen, K Fung, JM Brennan… - Proceedings of the …, 2020 - National Acad Sciences
Over the past decade, theranostic imaging has emerged as a powerful clinical tool in
oncology for identifying patients likely to respond to targeted therapies and for monitoring …
oncology for identifying patients likely to respond to targeted therapies and for monitoring …
Exosomes with immune modulatory features are present in human breast milk
C Admyre, SM Johansson, KR Qazi… - The Journal of …, 2007 - journals.aai.org
Breast milk is a complex liquid with immune-competent cells and soluble proteins that
provide immunity to the infant and affect the maturation of the infant's immune system …
provide immunity to the infant and affect the maturation of the infant's immune system …
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
I Martìn-Padura, S Lostaglio, M Schneemann… - The Journal of cell …, 1998 - rupress.org
Tight junctions are the most apical components of endothelial and epithelial intercellular
cleft. In the endothelium these structures play an important role in the control of paracellular …
cleft. In the endothelium these structures play an important role in the control of paracellular …
Proteomic profiling of exosomes: current perspectives
RJ Simpson, SS Jensen, JWE Lim - Proteomics, 2008 - Wiley Online Library
Exosomes are 40–100 nm membrane vesicles of endocytic origin secreted by most cell
types in vitro. Recent studies have shown that exosomes are also found in vivo in body fluids …
types in vitro. Recent studies have shown that exosomes are also found in vivo in body fluids …
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature
Exosomes are 40–100-nm-diameter nanovesicles of endocytic origin that are released from
diverse cell types. To better understand the biological role of exosomes and to avoid …
diverse cell types. To better understand the biological role of exosomes and to avoid …
Intestinal epithelial cells secrete exosome–like vesicles
G Van Niel, G Raposo, C Candalh, M Boussac… - Gastroenterology, 2001 - Elsevier
Background & Aims: Given the observations that intestinal epithelial cells (IECs) can present
antigens to CD4+ T lymphocytes and that professional antigen-presenting cells secrete …
antigens to CD4+ T lymphocytes and that professional antigen-presenting cells secrete …
SNAIL regulates interleukin-8 expression, stem cell–like activity, and tumorigenicity of human colorectal carcinoma cells
WL Hwang, MH Yang, ML Tsai, HY Lan, SH Su… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Some cancer cells have activities that are similar to those of stem
cells from normal tissues, and cell dedifferentiation correlates with poor prognosis. Little is …
cells from normal tissues, and cell dedifferentiation correlates with poor prognosis. Little is …