Mitofusins: disease gatekeepers and hubs in mitochondrial quality control by E3 ligases
M Escobar-Henriques, M Joaquim - Frontiers in physiology, 2019 - frontiersin.org
Mitochondria are dynamic organelles engaged in quality control and aging processes. They
constantly undergo fusion, fission, transport, and anchoring events, which empower …
constantly undergo fusion, fission, transport, and anchoring events, which empower …
E3 ubiquitin ligases neurobiological mechanisms: development to degeneration
Cells regularly synthesize new proteins to replace old or damaged proteins. Deposition of
various aberrant proteins in specific brain regions leads to neurodegeneration and aging …
various aberrant proteins in specific brain regions leads to neurodegeneration and aging …
Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS
Spinal motor axons traverse large distances to innervate target muscles, thus requiring local
control of cellular events for proper functioning. To interrogate axon-specific processes we …
control of cellular events for proper functioning. To interrogate axon-specific processes we …
A protein–miRNA biomic analysis approach to explore neuroprotective potential of nobiletin in human neural progenitor cells (hNPCs)
S Jahan, UA Ansari, AK Srivastava… - Frontiers in …, 2024 - frontiersin.org
Chemical-induced neurotoxicity is increasingly recognized to accelerate the development of
neurodegenerative disorders (NDs), which pose an increasing health burden to society …
neurodegenerative disorders (NDs), which pose an increasing health burden to society …
A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy
W Nonaka, T Takata, H Iwama… - Molecular …, 2022 - spandidos-publications.com
Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy described as a
syndrome of postural instability, supranuclear vertical gaze palsy, dysarthria, dystonic rigidity …
syndrome of postural instability, supranuclear vertical gaze palsy, dysarthria, dystonic rigidity …
Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects
C Liu, R Cao, Y Xu, T Li, F Li, S Chen, R Xu, K Sun - Genome Medicine, 2018 - Springer
Abstract Background Heterotaxy (Htx) syndrome comprises a class of congenital disorders
resulting from malformations in left-right body patterning. Approximately 90% of patients with …
resulting from malformations in left-right body patterning. Approximately 90% of patients with …
Cellular prion protein (PrPc): putative interacting partners and consequences of the interaction
H Miranzadeh Mahabadi, C Taghibiglou - International journal of …, 2020 - mdpi.com
Cellular prion protein (PrPc) is a small glycosylphosphatidylinositol (GPI) anchored protein
most abundantly found in the outer leaflet of the plasma membrane (PM) in the central …
most abundantly found in the outer leaflet of the plasma membrane (PM) in the central …
Proteasome‐mediated proteostasis: novel medicinal and pharmacological strategies for diseases
Proteins actively participate in a wide range of cellular physiological functions. But
aggregation of proteins results in cytotoxicity, and unwanted aggregation of misfolded …
aggregation of proteins results in cytotoxicity, and unwanted aggregation of misfolded …
Transcriptome sequencing analysis of circRNA in skeletal muscle between fast-and slow-growing chickens at embryonic stages
G Zhang, J Zhang, P Wu, X Ling, Q Wang, K Zhou, P Li… - Animals, 2022 - mdpi.com
Simple Summary Broilers provide a large amount of protein for human every year, in which
skeletal muscle contribute a major role. In recent years, circRNAs have been found to be …
skeletal muscle contribute a major role. In recent years, circRNAs have been found to be …
Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration
Proteins are ordered useful cellular entities, required for normal health and organism's
survival. The proteome is the absolute set of cellular expressed proteins, which regulates a …
survival. The proteome is the absolute set of cellular expressed proteins, which regulates a …