Cell-type deconvolution from DNA methylation: a review of recent applications

AJ Titus, RM Gallimore, LA Salas… - Human molecular …, 2017 - academic.oup.com
Recent advances in cell-type deconvolution approaches are adding to our understanding of
the biology underlying disease development and progression. DNA methylation (DNAm) …

[HTML][HTML] Air pollution-induced epigenetic changes: disease development and a possible link with hypersensitivity pneumonitis

S Mukherjee, S Dasgupta, PK Mishra… - … Science and Pollution …, 2021 - Springer
Air pollution is a serious threat to our health and has become one of the major causes of
many diseases including cardiovascular disease, respiratory disease, and cancer. The …

Identification of Smoking‐Associated Transcriptome Aberration in Blood with Machine Learning Methods

FM Huang, QL Ma, JX Ren, JR Li… - BioMed research …, 2023 - Wiley Online Library
Long‐term cigarette smoking causes various human diseases, including respiratory
disease, cancer, and gastrointestinal (GI) disorders. Alterations in gene expression and …

Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence

RH Mulder, A Neumann, CAM Cecil… - Human molecular …, 2021 - academic.oup.com
DNA methylation (DNAm) is known to play a pivotal role in childhood health and
development, but a comprehensive characterization of genome-wide DNAm trajectories …

Cigarette smoke-induced alterations in blood: A review of research on DNA methylation and gene expression.

CP Silva, HM Kamens - Experimental and clinical …, 2021 - psycnet.apa.org
Worldwide, smoking remains a threat to public health, causing preventable diseases and
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …

Evidence of epigenetic alterations in thrombosis and coagulation: A systematic review

MD Patsouras, PG Vlachoyiannopoulos - Journal of autoimmunity, 2019 - Elsevier
Thrombosis in the context of Cardiovascular disease (CVD) affects mainly the blood vessels
supplying the heart, brain and peripheries and it is the leading cause of death worldwide …

Environmental toxicology and omics: a question of sex

X Liang, A Feswick, D Simmons, CJ Martyniuk - Journal of proteomics, 2018 - Elsevier
Molecular initiating events and downstream transcriptional/proteomic responses provide
valuable information for adverse outcome pathways, which can be used predict the effects of …

Reprint of: Proteomics in cardiovascular diseases: Unveiling sex and gender differences in the era of precision medicine

R Baetta, M Pontremoli, AM Fernandez, CM Spickett… - Journal of …, 2018 - Elsevier
Cardiovascular diseases (CVDs) represent the most important cause of mortality in women
and in men. Contrary to the long-standing notion that the effects of the major risk factors on …

Creating and validating a DNA methylation-based proxy for interleukin-6

AJ Stevenson, DA Gadd, RF Hillary… - The Journals of …, 2021 - academic.oup.com
Background Studies evaluating the relationship between chronic inflammation and cognitive
functioning have produced heterogeneous results. A potential reason for this is the …

Pre‐diagnostic blood immune markers, incidence and progression of B‐cell lymphoma and multiple myeloma: Univariate and functionally informed multivariate …

R Vermeulen, F Saberi Hosnijeh… - … Journal of Cancer, 2018 - Wiley Online Library
Recent prospective studies have shown that dysregulation of the immune system may
precede the development of B‐cell lymphomas (BCL) in immunocompetent individuals …