Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Spinel ferrite nanoparticles and nanocomposites for biomedical applications and their toxicity

KK Kefeni, TAM Msagati, TTI Nkambule… - Materials Science and …, 2020 - Elsevier
This review focuses on the biomedical applications and toxicity of spinel ferrite nanoparticles
(SFNPs) with more emphasis on the recently published work. A critical review is provided on …

Overcoming barriers for siRNA therapeutics: from bench to bedside

MI Sajid, M Moazzam, S Kato, K Yeseom Cho… - Pharmaceuticals, 2020 - mdpi.com
The RNA interference (RNAi) pathway possesses immense potential in silencing any gene
in human cells. Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of …

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

HM Meng, H Liu, H Kuai, R Peng, L Mo… - Chemical Society …, 2016 - pubs.rsc.org
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

Aptamers as therapeutics

SM Nimjee, RR White, RC Becker… - Annual review of …, 2017 - annualreviews.org
Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and
are commonly produced by systematic evolution of ligands by exponential enrichment …

Application of semiconductor quantum dots in bioimaging and biosensing

IV Martynenko, AP Litvin, F Purcell-Milton… - Journal of Materials …, 2017 - pubs.rsc.org
In this review we present new concepts and recent progress in the application of
semiconductor quantum dots (QD) as labels in two important areas of biology, bioimaging …

Therapeutic applications of AS1411 aptamer, an update review

R Yazdian-Robati, P Bayat, F Oroojalian… - International journal of …, 2020 - Elsevier
Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …

Cancer active targeting by nanoparticles: a comprehensive review of literature

R Bazak, M Houri, S El Achy, S Kamel… - Journal of cancer research …, 2015 - Springer
Purpose Cancer is one of the leading causes of death, and thus, the scientific community
has but great efforts to improve cancer management. Among the major challenges in cancer …

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …