Photothermal therapy (PTT), which utilizes near‐infrared light‐absorbing agents to ablate
tumor, has emerged as a highly promising anticancer strategy and received intensive …

Appropriate autophagy has protective effects on ischemic nerve tissue, while excessive
autophagy may cause cell death. The inflammatory response plays an important role in the …

Inflammatory processes and microglia activation accompany most of the pathophysiological
diseases in the central nervous system. It is proven that glial pathology precedes and even …

Microglia activation is recognized as the hallmark of neuroinflammation. However, the
activation profile and phenotype changes of microglia during the process of retinal …

The NLRP3 inflammasome is a multi-molecular complex that acts as a molecular platform to
mediate caspase-1 activation, leading to IL-1β/IL-18 maturation and release in cells …

Sepsis is a leading cause of intensive care unit admission and death worldwide. Most
surviving patients show acute or chronic mental disorders, which are known as sepsis …

Background Berberine is a plant-derived alkaloid with potent anti-cancer activities.
Berberine may redirect the tumor-promoting immunosuppressive M2 macrophages, to …

Abstract NOD-like receptor 3 (NLRP3) plays critical roles in the initiation of inflammasome-
mediated inflammation in microglia, thus becomes an important therapeutic target of …

Sterile inflammatory processes are essential for the maintenance of central nervous system
homeostasis, but they also contribute to various neurological disorders, including …

Increasingly prevalent acute and chronic human brain diseases are scourges for the elderly.
Besides the lack of therapies, these ailments share a neuroinflammation that is …