Complement evasion strategies of viruses: an overview
Being a major first line of immune defense, the complement system keeps a constant vigil
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …
A double edged-sword-the complement system during SARS-CoV-2 infection
LE Santiesteban-Lores, TA Amamura, TF da Silva… - Life sciences, 2021 - Elsevier
In the past 20 years, infections caused by coronaviruses SARS-CoV, MERS-CoV and SARS-
CoV-2 have posed a threat to public health since they may cause severe acute respiratory …
CoV-2 have posed a threat to public health since they may cause severe acute respiratory …
Preoperative systemic immune-inflammation index predicts prognosis of patients with non-metastatic renal cell carcinoma: a propensity score-matched analysis
X Hu, YX Shao, ZQ Yang, WC Dou, SC Xiong… - Cancer cell …, 2020 - Springer
Background A novel systemic immune-inflammation index (SII), based on the neutrophils,
lymphocytes and platelet counts, is associated with the prognosis of several cancers. The …
lymphocytes and platelet counts, is associated with the prognosis of several cancers. The …
Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A (H1N1) 2009 …
A Rattan, SD Pawar, R Nawadkar, N Kulkarni… - PLoS …, 2017 - journals.plos.org
The pandemic influenza A (H1N1) 2009 virus caused significant morbidity and mortality
worldwide thus necessitating the need to understand the host factors that influence its …
worldwide thus necessitating the need to understand the host factors that influence its …
MiR-150-5p regulate T cell activation in severe aplastic anemia by targeting Bach2
Y Li, J Yu, F Wang, R Guo, H Xing, Y Chen… - Cell and Tissue …, 2021 - Springer
Abstract MiR-150-5p is an immune-related miRNA and elevated in the plasma of patients
with aplastic anemia (AA), but its role in T cell activation in patients with severe aplastic …
with aplastic anemia (AA), but its role in T cell activation in patients with severe aplastic …
Viral regulators of complement activation: structure, function and evolution
The complement system surveillance in the host is effective in controlling viral propagation.
Consequently, to subvert this effector mechanism, viruses have developed a series of …
Consequently, to subvert this effector mechanism, viruses have developed a series of …
The C18: 3n6/C22: 4n6 ratio is a good lipid marker of chronic kidney disease (CKD) progression
M Szczuko, M Kaczkan, S Małgorzewicz… - Lipids in health and …, 2020 - Springer
Background Chronic kidney disease (CKD) is a major challenge for public health due to
increased risk of cardiovascular diseases (CVD) and premature death. The aim of this study …
increased risk of cardiovascular diseases (CVD) and premature death. The aim of this study …
[HTML][HTML] Disabling complement regulatory activities of vaccinia virus complement control protein reduces vaccinia virus pathogenicity
Poxviruses encode a repertoire of immunomodulatory proteins to thwart the host immune
system. One among this array is a homolog of the host complement regulatory proteins that …
system. One among this array is a homolog of the host complement regulatory proteins that …
Mitochondrial Metabolism in Alveolar Macrophages of Patients Infected with HIV, Tuberculosis, and HIV/Tuberculosis
L Zhang, M Cai, B Su, Y Ma, Y Zhang - AIDS Research and Human …, 2024 - liebertpub.com
Tuberculosis (TB) is one of the most common opportunistic infections and is a leading cause
of mortality in patients with HIV and AIDS. HIV infection causes serious defects in the host …
of mortality in patients with HIV and AIDS. HIV infection causes serious defects in the host …
Species selectivity in poxviral complement regulators is dictated by the charge reversal in the central complement control protein modules
Variola and vaccinia viruses, the two most important members of the family Poxviridae, are
known to encode homologs of the human complement regulators named smallpox inhibitor …
known to encode homologs of the human complement regulators named smallpox inhibitor …