Circadian clocks, cognition, and Alzheimer's disease: synaptic mechanisms, signaling effectors, and chronotherapeutics

KR Hoyt, K Obrietan - Molecular neurodegeneration, 2022 - Springer
Modulation of basic biochemical and physiological processes by the circadian timing system
is now recognized as a fundamental feature of all mammalian organ systems. Within the …

The hippocampus and the regulation of human food intake.

RJ Stevenson, HM Francis - Psychological bulletin, 2017 - psycnet.apa.org
Human and animal data suggest that the hippocampus plays certain roles in regulating food
intake. However, its actual role may be far broader than currently envisaged, a claim …

HippoBellum: acute cerebellar modulation alters hippocampal dynamics and function

Z Zeidler, K Hoffmann… - Journal of …, 2020 - Soc Neuroscience
Here we examine what effects acute manipulation of the cerebellum, a canonically motor
structure, can have on the hippocampus, a canonically cognitive structure. In male and …

Circadian regulation of membrane physiology in neural oscillators throughout the brain

JR Paul, JA Davis, LK Goode, BK Becker… - European Journal of …, 2020 - Wiley Online Library
Twenty‐four‐hour rhythmicity in physiology and behavior are driven by changes in
neurophysiological activity that vary across the light–dark and rest‐activity cycle. Although …

The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy

KJ Debski, N Ceglia, A Ghestem, AI Ivanov… - Science …, 2020 - science.org
Gene and protein expressions display circadian oscillations, which can be disrupted in
diseases in most body organs. Whether these oscillations occur in the healthy hippocampus …

[HTML][HTML] Contributions of the lateral habenula to circadian timekeeping

B Baño-Otálora, HD Piggins - Pharmacology Biochemistry and Behavior, 2017 - Elsevier
Over the past 20 years, substantive research has firmly implicated the lateral habenula in
myriad neural processes including addiction, depression, and sleep. More recently …

基于红外相机技术的天津城市地栖哺乳动物昼夜活动节律评价

卢佳玉, 石小亿, 多立安, 王天明, 李治霖 - 生物多样性, 2024 - biodiversity-science.net
城市化进程可导致自然栖息地大量丧失和破碎化, 继而影响野生动物的活动节律和生态位关系.
因此对各物种活动节律和生态位关系的精准评价是理解城市生物多样性维持机制的关键基础 …

Neurochemically and hodologically distinct ascending VGLUT3 versus serotonin subsystems comprise the r2-Pet1 median raphe

RA Senft, ME Freret, N Sturrock… - Journal of …, 2021 - Soc Neuroscience
Brainstem median raphe (MR) neurons expressing the serotonergic regulator gene Pet1
send collateralized projections to forebrain regions to modulate affective, memory-related …

Optogenetic investigation of arousal circuits

SM Tyree, L De Lecea - International journal of molecular sciences, 2017 - mdpi.com
Modulation between sleep and wake states is controlled by a number of heterogeneous
neuron populations. Due to the topological proximity and genetic co-localization of the …

Prefrontal and hippocampal theta rhythm show anxiolytic‐like changes during periaqueductal‐elicited “panic” in rats

C Silva, CK Young, N McNaughton - Hippocampus, 2022 - Wiley Online Library
Anxiety and panic are both elicited by threat and co‐occur clinically. But, at the neural level,
anxiety appears to inhibit the generation of panic; and vice versa. Anxiety and panic are …