Considerable changes have occurred in the management of differentiated thyroid cancer
(DTC) during the past four decades, based on improved knowledge of the biology of DTC …

Iodine is a micronutrient needed for the production of thyroid hormones, which regulate
metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid …

Diffuse intrinsic pontine glioma (DIPG) remains a fatal brainstem tumor demanding
innovative therapies. As B7-H3 (CD276) is expressed on central nervous system (CNS) …

Cancer genomics research aims to advance personalized oncology by finding and targeting
specific genetic alterations associated with cancers. In genome-driven oncology, treatments …

Thyroid disorders are common, affecting more than 10% of people in the US, and laboratory
tests are integral in the management of these conditions. The repertoire of thyroid tests …

Context Modern management of differentiated thyroid cancer requires individualized care
plans that tailor the intensity of therapy and follow-up to the estimated risks of recurrence …

BACKGROUND Historically the success of mass spectrometry in the clinical laboratory has
focused on drugs of abuse confirmations, newborn screening, and steroid analysis. Clinical …

Tumor tissue processing methodologies in combination with data‐independent acquisition
mass spectrometry (DIA‐MS) have emerged that can comprehensively analyze the …

Objective Thyroglobulin measurement is the cornerstone of modern management of
differentiated thyroid cancer, with clinical decisions on treatment and follow-up based on the …

The treatment paradigm for thyroid cancer has shifted from a one-size-fits-all approach to
more personalized protocols that range from active surveillance to total thyroidectomy …