Highlights•Amine transaminases are extremely important for the synthesis of chiral primary
amines.•Progress has been made towards developing transaminases with broader …

Performing one‐pot multi‐catalysis reactions is a revolutionary tool for multistep synthesis,
representing a fast‐developing theme in catalysis field. To develop cascade reactions …

As the enzyme toolbox for biocatalysis has expanded, so has the potential for the
construction of powerful enzymatic cascades for efficient and selective synthesis of target …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

Toxoplasma gondii is a parasite that replicates within a specialized compartment called the
parasitophorous vacuole (PV), which is surrounded by the PV membrane (PVM). To obtain …

Engineering biotechnological microorganisms to use methanol as a feedstock for
bioproduction is a major goal for the synthetic metabolism community. Here, we aim to …

Abstract L‐Homophenylalanine (L‐HPA) is a vital building block for the synthesis of
numerous chiral drugs. However, the high cost of starting materials limits the industrial …

Aldolases are powerful C–C bond-forming enzymes in biocatalysis because of their
unparalleled stereoselectivity, the ease with which reactions that do not require cofactor …

Early evolution benefited from a complex network of reactions involving multiple C− C bond
forming and breaking events that were critical for primitive metabolism. Nature gradually …

Enzymes are renowned for their catalytic efficiency and selectivity. Despite the wealth of
carbon–carbon bond-forming transformations in traditional organic chemistry and nature …