Melatonin, endocrine pancreas and diabetes

E Peschke - Journal of pineal research, 2008 - Wiley Online Library
Melatonin influences insulin secretion both in vivo and in vitro.(i) The effects are MT1‐and
MT2‐receptor‐mediated.(ii) They are specific, high‐affinity, pertussis‐toxin‐sensitive, Gi …

[HTML][HTML] Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes

H Kanzaki, F Shinohara, I Kanako, Y Yamaguchi… - Redox biology, 2016 - Elsevier
It has been reported that reactive oxygen species (ROS), such as hydrogen peroxide and
superoxide, take part in osteoclast differentiation as intra-cellular signaling molecules. The …

Synthesis, characterization, molecular dynamic simulation, and biological assessment of cinnamates linked to imidazole/benzimidazole as a CYP51 inhibitor

AR Zala, DP Rajani, I Ahmad, H Patel… - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract A class of 2-(1 H-imidazol-1-yl)-1-phenylethyl cinnamates 6a-6j and 2-(1 H-benzo
[d] imidazol-1-yl)-1-phenylethyl cinnamates 7a-7j were synthesized, and their synthesis was …

Benzimidazoles in helminthiasis chemotherapy: Developments and challenges

P Pattanayak, D Panigrahi, S Kumari, HN Yadav… - Journal of Molecular …, 2024 - Elsevier
Globally, helminthiasis is one of the most prevalent causes of mortality and morbidity and
threatens humans and livestock. An effective anthelmintic vaccine is also lacking. As a …

Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles

A Baldisserotto, M Demurtas, I Lampronti… - Bioorganic …, 2020 - Elsevier
Three series of arylbenzimidazole derivatives 3–40, 45 have been simply synthesized and
tested for their antioxidant capacity. The 2-arylbenzimidazoles were tested against various …

Evaluation of the mineral composition, phytochemical and proximate constituents of three culinary spices in Nigeria: a comparative study

UF Evuen, NP Okolie, A Apiamu - Scientific Reports, 2022 - nature.com
Spices are prolific sources of phytochemicals of pharmaceutical and nutritional importance.
They have been employed for centuries in the treatment of various maladies, in cuisines …

Synthesis, antimicrobial and antiviral activity of substituted benzimidazoles

D Sharma, B Narasimhan, P Kumar… - Journal of Enzyme …, 2009 - Taylor & Francis
In the present study we have synthesized (4-nitrophenyl)-[2-(substituted phenyl)-
benzoimidazol-1-yl]-methanones,(2-bromophenyl)-[2-(substituted phenyl)-benzoimidazol-1 …

Design, synthesis, antioxidant properties and mechanism of action of new N, N′-disubstituted benzimidazole-2-thione hydrazone derivatives

NO Anastassova, DY Yancheva, AT Mavrova… - Journal of Molecular …, 2018 - Elsevier
New series of N, N′-disubstituted benzimidazole-2-thione were synthesized by introduction
of hydrazone moiety in the side chains. The toxicological potential of studied compounds …

Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses

S Huang, H Deng, X Wei, J Zhang - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Terahertz time-domain spectroscopy is an analytical method using terahertz time-domain
pulses to study the physical and chemical properties of substances. It has strong potential for …

[HTML][HTML] Hepatotoxicity and antioxidant activity of some new N, N′-disubstituted benzimidazole-2-thiones, radical scavenging mechanism and structure-activity …

NO Anastassova, AT Mavrova, DY Yancheva… - Arabian Journal of …, 2018 - Elsevier
A new method for the synthesis of 1, 3-disubstituted benzimidazole derivatives was
developed using aza-Michael addition. The target compounds were synthesized in good …