The implications of drug-polymer interactions on the physical stability of amorphous solid dispersions

M Bookwala, PLD Wildfong - Pharmaceutical Research, 2023 - Springer
Amorphous solid dispersions (ASDs) are a formulation and development strategy that can
be used to increase the apparent aqueous solubility of poorly water-soluble drugs. Their …

Antibacterial hydroxypropyl methyl cellulose edible films containing nanoemulsions of Thymus daenensis essential oil for food packaging

R Moghimi, A Aliahmadi, H Rafati - Carbohydrate polymers, 2017 - Elsevier
Edible films containing essential oils (EO) as natural antibacterial agents are promising
systems for food preservation. In this work, nanoemulsions of Thymus daenensis EO (wild; …

Interaction between mucoadhesive cellulose derivatives and Pluronic F127: Investigation on the micelle structure and mucoadhesive performance

JB da Silva, RS Dos Santos, MB da Silva… - Materials Science and …, 2021 - Elsevier
Abstract Systems composed of bioadhesive and thermoresponsive polymers can combine in
situ gelation with bio/mucoadhesion, enhancing retention of topically applied drugs. The …

Synthesis and characterization of slow-release fertilizer hydrogel based on hydroxy propyl methyl cellulose, polyvinyl alcohol, glycerol and blended paper

SA Kareem, I Dere, DT Gungula, FP Andrew… - Gels, 2021 - mdpi.com
In this study, biodegradable slow-release fertilizer (SRF) hydrogels were synthesized from
hydroxyl propyl methyl cellulose (HPMC), polyvinyl alcohol (PVA), glycerol and urea (SRF1) …

Solid dispersions of gefitinib prepared by spray drying with improved mucoadhesive and drug dissolution properties

WW Mustafa, J Fletcher, M Khoder, RG Alany - AAPS PharmSciTech, 2022 - Springer
Gefitinib is a tyrosine kinase inhibitor that is intended for oral administration yet suffers poor
bioavailability along with undesirable side effects. To enhance its solubility and allow colon …

Design, development and evaluation of Resveratrol transdermal patches for breast cancer therapy

S Gadag, R Narayan, Y Nayak, S Garg… - International Journal of …, 2023 - Elsevier
Resveratrol (RVT) is a polyphenolic phytoestrogen which has shown antiproliferative activity
in breast cancer. However, its low bioavailability and short half-life have restricted its use …

Fabrication of 3D Printed, Core‐and‐Shell Implants as Controlled Release Systems for Local siRNA Delivery

DB Mahmoud, C Wölk… - Advanced Healthcare …, 2023 - Wiley Online Library
The development and clinical translation of small interfering RNA (siRNA) therapies remains
challenging owing to their poor pharmacokinetics. 3D printing technology presents a great …

Combination of beeswax and nanoclay on barriers, sorption isotherm and mechanical properties of hydroxypropyl methylcellulose-based composite films

P Klangmuang, R Sothornvit - LWT-Food Science and Technology, 2016 - Elsevier
Hydroxypropyl methylcellulose (HPMC)-based films are widely used but there is still a need
to improve their properties due to their hydrophilic nature. Beeswax and nanoclay are …

Characterization of Calotropis gigantiea plant leaves biomass-based bioplasticizers for biofilm applications

SS Chandraraj, I Suyambulingam, N Edayadulla… - Heliyon, 2024 - cell.com
The present surge in environmental consciousness has pushed for the use of biodegradable
plasticizers, which are sustainable and abundant in plant resources. As a result of their …

An Investigation into the Influence of Filler Piper nigrum Leaves Extract on Physicochemical and Antimicrobial Properties of Chitosan/Poly (Vinyl Alcohol) Blend Films

D Kasai, R Chougale, S Masti, R Chalannavar… - Journal of Polymers and …, 2019 - Springer
The influence of Piper nigrum (P. nigrum) leaves extract on structural and physicochemical
properties of chitosan/poly (vinyl alcohol)(CH/PVA) blend films were studied. The hypothesis …