The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …

Inositols are sugar-like compounds that are widely distributed in nature and are a part of
membrane molecules, participating as second messengers in several cell-signaling …

Working memory relies on the dorsolateral prefrontal cortex (dlPFC), where microcircuits of
pyramidal neurons enable persistent firing in the absence of sensory input, maintaining …

Approximately 50 million people have epilepsy, making it the most common chronic and
severe neurological disease worldwide, with increased risk of mortality and psychological …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

In recent years, numerous studies of gene regulation mechanisms have emerged in
neuroscience. Epigenetic modifications, described as heritable but reversible changes …

Neurological disorders including depression, anxiety, post-traumatic stress disorder (PTSD),
schizophrenia, autism and epilepsy are associated with an increased incidence of …

Bipolar disorder (BD) is a multifactorial illness thought to result from an interaction between
genetic susceptibility and environmental stimuli. Epigenetic mechanisms, including DNA …

Glycogen synthase kinase 3β (GSK3) is a multifaceted serine/threonine (S/T) kinase
expressed in all eukaryotic cells. GSK3β is highly enriched in neurons in the central nervous …