Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

JA Caminero, G Sotgiu, A Zumla… - The Lancet infectious …, 2010 - thelancet.com
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally
thought to have high mortality rates. However, many cases can be treated with the right …

Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis

EW Orenstein, S Basu, NS Shah… - The Lancet infectious …, 2009 - thelancet.com
Multidrug-resistant (MDR) tuberculosis is a growing clinical and public-health concern. To
evaluate existing evidence regarding treatment regimens for MDR tuberculosis, we used a …

Frequency and factors associated with adverse events among multi-drug resistant tuberculosis patients in Pakistan: A retrospective study

M Atif, W Ahmed, M Nouman Iqbal, N Ahmad… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of multi-drug resistant tuberculosis (MDR-TB) for a prolonged period
with comparatively less effective and more toxic second-line anti-TB drugs is associated with …

Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis

Z Lan, N Ahmad, P Baghaei, L Barkane… - The Lancet …, 2020 - thelancet.com
Background Treatment of multidrug-resistant tuberculosis requires long-term therapy with a
combination of multiple second-line drugs. These drugs are associated with numerous …

High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses

A Piubello, SH Harouna… - … of Tuberculosis and …, 2014 - ingentaconnect.com
SETTING: Niger National Tuberculosis Programme. Regions supported by the Damien
Foundation. OBJECTIVE: To evaluate the effectiveness of a short-course standardised …

Adverse drug reactions in tuberculosis and management

R Prasad, A Singh, N Gupta - Indian Journal of Tuberculosis, 2019 - Elsevier
Background Treatment of drug susceptible tuberculosis (DS-TB) requires regimens
containing first line drugs (FLDs') whereas drug resistant tuberculosis (DR-TB) are treated …

[HTML][HTML] Antituberculosis drugs: drug interactions, adverse effects, and use in special situations-part 1: first-line drugs

MA Arbex, MCL Varella, HR Siqueira… - Jornal Brasileiro de …, 2010 - SciELO Brasil
Os objetivos principais do tratamento da tuberculose são curar o paciente e minimizar a
possibilidade de transmissão do bacilo para indivíduos saudáveis. Reações adversas ou …

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement

J Domínguez, EC Boettger, D Cirillo… - … of tuberculosis and …, 2016 - ingentaconnect.com
The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as …

Predictors of poor outcomes among patients treated for multidrug-resistant tuberculosis at DOTS-plus projects

EV Kurbatova, A Taylor, VM Gammino, J Bayona… - Tuberculosis, 2012 - Elsevier
The Objective of this analysis was to identify predictors of death, failure, and default among
MDR-TB patients treated with second-line drugs in DOTS-plus projects in Estonia, Latvia …

Safety and tolerability profile of second-line anti-tuberculosis medications

G Ramachandran, S Swaminathan - Drug safety, 2015 - Springer
Tuberculosis (TB) remains a major public health problem, representing the second leading
cause of death from infectious diseases globally, despite being nearly 100% curable …