Cannabidiol for pain treatment: focus on pharmacology and mechanism of action

J Mlost, M Bryk, K Starowicz - International journal of molecular sciences, 2020 - mdpi.com
Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

[HTML][HTML] Molecular targets of cannabidiol in neurological disorders

CI Bih, T Chen, AVW Nunn, M Bazelot, M Dallas… - …, 2015 - Elsevier
Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

Molecular pharmacology of phytocannabinoids

SE Turner, CM Williams, L Iversen… - … : unraveling the complex …, 2017 - Springer
Cannabis sativa has been used for recreational, therapeutic and other uses for thousands of
years. The plant contains more than 120 C 21 terpenophenolic constituents named …

Cannabidiol (CBD) is a novel inhibitor for exosome and microvesicle (EMV) release in cancer

US Kosgodage, R Mould, AB Henley… - Frontiers in …, 2018 - frontiersin.org
Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells
and involved in intercellular communication through transfer of proteins and genetic …

Regulatory effects of cannabidiol on mitochondrial functions: a review

JZ Chan, RE Duncan - Cells, 2021 - mdpi.com
Cannabidiol (CBD) is part of a group of phytocannabinoids derived from Cannabis sativa.
Initial work on CBD presumed the compound was inactive, but it was later found to exhibit …

Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system

MS Aymerich, E Aso, MA Abellanas, RM Tolon… - Biochemical …, 2018 - Elsevier
The endocannabinoid system (ECS) exerts a modulatory effect of important functions such
as neurotransmission, glial activation, oxidative stress, or protein homeostasis …

Cannabinoids in medicine: a multifaceted exploration of types, therapeutic applications, and emerging opportunities in neurodegenerative diseases and cancer …

V Voicu, FM Brehar, C Toader, RA Covache-Busuioc… - Biomolecules, 2023 - mdpi.com
In this review article, we embark on a thorough exploration of cannabinoids, compounds that
have garnered considerable attention for their potential therapeutic applications. Initially, this …

Geotemporospatial and causal inference epidemiological analysis of US survey and overview of cannabis, cannabidiol and cannabinoid genotoxicity in relation to …

AS Reece, GK Hulse - BMC pediatrics, 2022 - Springer
Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …

Cannabinoid signaling in health and disease

Y Lu, HD Anderson - Canadian journal of physiology and …, 2017 - cdnsciencepub.com
Cannabis sativa has long been used for medicinal purposes. To improve safety and efficacy,
compounds from C. sativa were purified or synthesized and named under an umbrella group …

Effects of cannabidiol on exercise physiology and bioenergetics: a randomised controlled pilot trial

A Sahinovic, C Irwin, PT Doohan, RC Kevin… - Sports Medicine …, 2022 - Springer
Background Cannabidiol (CBD) has demonstrated anti-inflammatory, analgesic, anxiolytic
and neuroprotective effects that have the potential to benefit athletes. This pilot study …