Dimethyl fumarate and curcumin attenuate hepatic ischemia/reperfusion injury via Nrf2/HO-1 activation and anti-inflammatory properties

SG Ibrahim, SZ El-Emam, EA Mohamed… - International …, 2020 - Elsevier
Background Hepatic ischemia/reperfusion (I/R) injury occurs in different clinical settings as
hepatic transplantation, and different types of shock. I/R injury is the main cause of hepatic …

Cr (VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway

Y Zhang, F Xiao, X Liu, K Liu, X Zhou, C Zhong - Toxicology in Vitro, 2017 - Elsevier
The occupational and environmental toxicant hexavalent chromium [Cr (VI)] can cause
severe damage to the liver; however, the exact mechanisms associated with its toxicity have …

Ellagic acid ameliorates hexavalent chromium-induced renal toxicity by attenuating oxidative stress, suppressing TNF-α and protecting mitochondria

MY Cuevas-Magaña, CC Vega-García… - Toxicology and applied …, 2022 - Elsevier
Nephrotoxicity is an important adverse effect of oxidative stress induced by hexavalent
chromium [Cr (VI)]. The effect of ellagic acid, a dietary polyphenolic compound with potent …

Mitochondrial biogenesis in response to chromium (VI) toxicity in human liver cells

X Zhong, RCS Sá, C Zhong - International journal of molecular sciences, 2017 - mdpi.com
Hexavalent chromium (Cr (VI)) is a ubiquitous environmental pollutant, which poses a threat
to human public health. Recent studies have shown that mitochondrial biogenesis can be …

Autoimmune hepatitis associated with turmeric consumption

BS Lee, T Bhatia, CT Chaya, R Wen… - ACG Case Reports …, 2020 - journals.lww.com
Turmeric is a popular herbal dietary supplement that has been considered safe and even
shown to have hepatoprotective properties. In the recent times, however, there have been a …

Oxidative stress markers and histological analysis in diverse organs from rats treated with a hepatotoxic dose of Cr (VI): effect of curcumin

WR García-Niño, ZL Zatarain-Barrón… - Biological trace element …, 2015 - Springer
Abstract Hexavalent chromium [Cr (VI)] compounds are extremely toxic and carcinogenic.
Despite the vast quantity of reports about Cr (VI) toxicity, the information regarding its effects …

Curcumin prevents paracetamol-induced liver mitochondrial alterations

LF Granados-Castro… - Journal of Pharmacy …, 2016 - academic.oup.com
Objective In the present study was evaluated if curcumin is able to attenuate paracetamol
(PCM)-induced mitochondrial alterations in liver of mice. Methods Mice (n= 5–6/group) …

[HTML][HTML] Effects of chromium picolinate on fat deposition, activity and genetic expression of lipid metabolism-related enzymes in 21 day old Ross broilers

G Chen, Z Gao, W Chu, Z Cao, C Li… - … -Australasian journal of …, 2018 - ncbi.nlm.nih.gov
Objective This experiment was conducted to investigate the effects of chromium picolinate
(CrP) on fat deposition, genetic expression and enzymatic activity of lipid metabolism-related …

HBM4EU chromates study: urinary metabolomics study of workers exposed to hexavalent chromium

L Kozłowska, T Santonen, RC Duca, L Godderis… - Metabolites, 2022 - mdpi.com
Exposure to hexavalent chromium Cr (VI) may occur in several occupational activities,
placing workers in many industries at risk for potential related health outcomes. Untargeted …

[HTML][HTML] Cardiolipin mediates curcumin interactions with mitochondrial membranes

S Ben-Zichri, S Kolusheva, M Danilenko… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Curcumin, the main molecular ingredient of the turmeric spice, has been reported to exhibit
therapeutic properties for varied diseases and pathological conditions. While curcumin …