Subclinical depressive symptoms are associated with increased risk of Alzheimer's disease
(AD), but the brain mechanisms underlying this relationship are still unclear. We aimed to …

Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …

Recent neuroimaging studies have characterized the pathophysiology of late-life depression
(LLD) as a dysfunction of the brain networks involved in the regulation of emotion …

Background Depression's relationship with cerebral abnormalities and cognitive decline is
temporally dynamic. Despite clear clinical utility, understanding depression's effect on …

Introduction Obstructive sleep apnea (OSA) affects approximately 10% of adults, and alters
brain gray and white matter. Psychological and physiological symptoms of the disorder are …

Metformin, the most commonly prescribed drug for the treatment of diabetes, is increasingly
used during pregnancy to address various disorders such as diabetes, obesity …

A cross-sectional study was conducted to evaluate patterns of gray matter changes in
cognitively normal elderly adults with mild behavioral impairment (MBI). Sixteen MBI patients …

Early adversity has been related to brain structure alterations and to an increased risk of
psychiatric disorders. The orbitofrontal cortex (OFC) is a key region for emotional …

Anxiety and depressive symptoms may predispose individuals to sleep disturbance.
Understanding how these emotional symptoms affect sleep quality, especially the …

Background: Improving mental health in older adults is a priority in our aging societies.
Anxiety and depressive symptoms are associated with impaired well-being, higher risk of …