In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …

Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …

Alterations in stiffness of the trabecular meshwork (TM) may play an important role in primary
open-angle glaucoma (POAG), the second leading cause of blindness. Specifically, certain …

Purpose: Treatment with corticosteroids can result in ocular hypertension and may lead to
the development of steroid-induced glaucoma. The extent to which biomechanical changes …

Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called
steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma …

The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

Epithelial cells rapidly adapt their behaviour in response to increasing tissue demands.
However, the processes that finely control these cell decisions remain largely unknown. The …

Exosomes are membrane-bound tiny particles that are released by all live cells that contain
multiple signal molecules and extensively participate in numerous normal physical activities …

Glaucoma is a leading cause of blindness worldwide and results from damage to the optic
nerve. Currently, intraocular pressure is the only treatable risk factor. Changes in aqueous …

Glaucoma is a progressive neurodegenerative disease which constitutes the main frequent
cause of irreversible blindness. Recent findings have shown that oxidative stress …