Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …

Perivascular spaces that are visible on magnetic resonance imaging (MRI) are a
neuroimaging marker of cerebral small vessel disease. Their location may relate to the type …

Importance With advancing age, an increased visibility of perivascular spaces (PVSs) on
magnetic resonance imaging (MRI) is hypothesized to represent impaired drainage of …

Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

Objective To determine whether severe perivascular space (PVS) dilation is associated with
longitudinal cognitive decline and incident dementia over 4 and 8 years, respectively, we …

Objectives To investigate glymphatic function in Alzheimer's disease (AD) using the diffusion
tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the …

Amyloid-β (Aβ) plaques are a key histopathological hallmark of Alzheimer's disease (AD),
and soluble Aβ species are believed to play an important role in the clinical development of …