Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease
G Ganguly, S Chakrabarti, U Chatterjee… - Drug design …, 2017 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …
of the elderly people that have devastating effects in terms of morbidity and mortality. The …
Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation
M Jazvinšćak Jembrek, PR Hof… - Oxidative medicine and …, 2015 - Wiley Online Library
Alzheimer's disease (AD), the most common chronic and progressive neurodegenerative
disorder, is characterized by extracellular deposits of amyloid β‐peptides (Aβ) and …
disorder, is characterized by extracellular deposits of amyloid β‐peptides (Aβ) and …
Oxidative stress, neuroinflammation, and NADPH oxidase: implications in the pathogenesis and treatment of Alzheimer's disease
NADPH oxidase as an important source of intracellular reactive oxygen species (ROS) has
gained enormous importance over the years, and the detailed structures of all the …
gained enormous importance over the years, and the detailed structures of all the …
Enhanced ROS production and oxidative damage in subcutaneous white adipose tissue mitochondria in obese and type 2 diabetes subjects
M Chattopadhyay, VK Khemka, G Chatterjee… - Molecular and cellular …, 2015 - Springer
Oxidative stress in the insulin target tissues has been implicated in the pathophysiology of
type 2 diabetes. The study has examined the oxidative stress parameters in the …
type 2 diabetes. The study has examined the oxidative stress parameters in the …
Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease
M Pennisi, R Crupi, R Di Paola… - Journal of …, 2017 - Wiley Online Library
Alzheimer disease (AD) is a progressive neurodegenerative disorder leading to cognitive
decline, neuropsychiatric symptoms, disability, caregiver burden, and premature death. It …
decline, neuropsychiatric symptoms, disability, caregiver burden, and premature death. It …
[HTML][HTML] Metabolic risk factors of sporadic Alzheimer's disease: implications in the pathology, pathogenesis and treatment
S Chakrabarti, VK Khemka, A Banerjee… - Aging and …, 2015 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the major cause of dementia among the elderly world-
wide, manifests in familial and sporadic forms, and the latter variety accounts for the majority …
wide, manifests in familial and sporadic forms, and the latter variety accounts for the majority …
[HTML][HTML] Neuroprotective effect of caffeic acid phenethyl ester in a mouse model of Alzheimer's disease involves Nrf2/HO-1 pathway
Alzheimer's disease (AD) is a progressive pathology, where dementia symptoms gradually
worsen over a number of years. The hallmarks of AD, such as amyloid β-peptide (Aβ) in …
worsen over a number of years. The hallmarks of AD, such as amyloid β-peptide (Aβ) in …
Islet amyloid polypeptide: a partner in crime with Aβ in the pathology of alzheimer's disease
AF Raimundo, S Ferreira, IC Martins… - Frontiers in molecular …, 2020 - frontiersin.org
Diabetes affects hundreds of millions of patients worldwide. Despite the advances in
understanding the disease and therapeutic options, it remains a leading cause of death and …
understanding the disease and therapeutic options, it remains a leading cause of death and …
Inhibition of IAPP aggregation and toxicity by natural products and derivatives
A Pithadia, JR Brender, CA Fierke… - Journal of diabetes …, 2016 - Wiley Online Library
Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen
in some diabetes patients, are a likely causative agent for pancreatic beta‐cell toxicity …
in some diabetes patients, are a likely causative agent for pancreatic beta‐cell toxicity …
Environmental enrichment and exercise are better than social enrichment to reduce memory deficits in amyloid beta neurotoxicity
MG Prado Lima, HL Schimidt… - Proceedings of the …, 2018 - National Acad Sciences
Recently, nongenetic animal models to study the onset and development of Alzheimer's
disease (AD) have appeared, such as the intrahippocampal infusion of peptides present in …
disease (AD) have appeared, such as the intrahippocampal infusion of peptides present in …