Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis

WJ Lynch, AB Peterson, V Sanchez, J Abel… - … & Biobehavioral Reviews, 2013 - Elsevier
Physical activity, and specifically exercise, has been suggested as a potential treatment for
drug addiction. In this review, we discuss clinical and preclinical evidence for the efficacy of …

[HTML][HTML] An evaluation of the evidence that methamphetamine abuse causes cognitive decline in humans

AC Dean, SM Groman, AM Morales… - …, 2013 - nature.com
Methamphetamine (MA) is one of the most commonly abused illicit substances worldwide.
Among other problems, abuse of the drug has been associated with reduced cognitive …

Molecular, behavioral, and physiological consequences of methamphetamine neurotoxicity: implications for treatment

A Moszczynska, SP Callan - Journal of pharmacology and experimental …, 2017 - ASPET
Understanding the relationship between the molecular mechanisms underlying neurotoxicity
of high-dose methamphetamine (METH) and related clinical manifestations is imperative for …

The science of making drug-addicted animals

SH Ahmed - Neuroscience, 2012 - Elsevier
Research involving animal models of drug addiction can be viewed as a sort of reverse
psychiatry. Contrary to clinicians who seek to treat addicted people to become and remain …

Neurodevelopmental origins of substance use disorders: Evidence from animal models of early‐life adversity and addiction

SC Levis, TZ Baram, SV Mahler - European Journal of …, 2022 - Wiley Online Library
Addiction is a chronic relapsing disorder with devastating personal, societal, and economic
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …

Sex differences in escalation of methamphetamine self-administration: cognitive and motivational consequences in rats

CM Reichel, CH Chan, SM Ghee, RE See - Psychopharmacology, 2012 - Springer
Rationale Male rats escalate methamphetamine (meth) intake during long-access meth self-
administration, show enhanced reinstatement of meth-seeking, and exhibit meth-induced …

Animal models of substance abuse and addiction: implications for science, animal welfare, and society

WJ Lynch, KL Nicholson, ME Dance… - Comparative …, 2010 - ingentaconnect.com
Substance abuse and addiction are well recognized public health concerns, with 2 NIH
institutes (the National Institute on Drug Abuse and the National Institute on Alcohol Abuse …

Methamphetamine addiction: involvement of CREB and neuroinflammatory signaling pathways

IN Krasnova, Z Justinova, JL Cadet - Psychopharmacology, 2016 - Springer
Rationale and objectives Addiction to psychostimulant methamphetamine (METH) remains a
major public health problem in the world. Animal models that use METH self-administration …

Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors

EJ Shin, DK Dang, TV Tran, HQ Tran, JH Jeong… - Archives of Pharmacal …, 2017 - Springer
Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is
associated with extensive neurodegeneration, psychosis, and cognitive impairment …

Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats

DS Carson, JL Cornish, AJ Guastella, GE Hunt… - …, 2010 - Elsevier
There is emerging evidence that the neuropeptide oxytocin may be utilised as a treatment
for various psychopathologies, including drug addictions. Here we used an animal model to …