Analytical techniques for the characterization of nanoparticles for mRNA delivery

SS Nogueira, E Samaridou, J Simon, S Frank… - European Journal of …, 2024 - Elsevier
Nanotechnology-assisted RNA delivery has gotten a tremendous boost over the last decade
and made a significant impact in the development of life-changing vaccines and …

Effect of lipid composition on RNA-Lipid nanoparticle properties and their sensitivity to thin-film freezing and drying

K AboulFotouh, B Southard, HM Dao, H Xu… - International Journal of …, 2024 - Elsevier
A library of 16 lipid nanoparticle (LNP) formulations with orthogonally varying lipid molar
ratios was designed and synthesized, using polyadenylic acid [poly (A)] as a model for …