Interplay of oxidative stress, cellular communication and signaling pathways in cancer
Cancer remains a significant global public health concern, with increasing incidence and
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …
Lactic acid bacteria-derived exopolysaccharide: Formation, immunomodulatory ability, health effects, and structure-function relationship
J Zhang, Y Xiao, H Wang, H Zhang, W Chen… - Microbiological …, 2023 - Elsevier
Exopolysaccharides (EPSs) synthesized by lactic acid bacteria (LAB) have implications for
host health and act as food ingredients. Due to the variability of LAB-EPS (lactic acid …
host health and act as food ingredients. Due to the variability of LAB-EPS (lactic acid …
Modulation of NRF2: biological dualism in cancer, targets and possible therapeutic applications
M Gallorini, S Carradori, E Panieri, M Sova… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: The nuclear factor erythroid 2-related factor 2 (NRF2)-Kelch-like ECH-
associated protein 1 (KEAP1) system is a master regulator of redox homeostasis and cell …
associated protein 1 (KEAP1) system is a master regulator of redox homeostasis and cell …
Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models
Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …
patients. However, it is accompanied by diverse neurological complications which are …
Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration
HJ Kim, JM Saikia, KMA Monte, E Ha… - Neuron, 2023 - cell.com
Despite substantial progress in understanding the biology of axon regeneration in the CNS,
our ability to promote regeneration of the clinically important corticospinal tract (CST) after …
our ability to promote regeneration of the clinically important corticospinal tract (CST) after …
Immunological dimensions of neuroinflammation and microglial activation: exploring innovative immunomodulatory approaches to mitigate neuroinflammatory …
L Fornari Laurindo, J Aparecido Dias… - Frontiers in …, 2024 - frontiersin.org
The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …
Platelets rich plasma increases antioxidant defenses of tenocytes via Nrf2 signal pathway
A Tognoloni, D Bartolini, M Pepe, A Di Meo… - International Journal of …, 2023 - mdpi.com
Tendinopathies are common disabling conditions in equine and human athletes. The
etiology is still unclear, although reactive oxygen species (ROS) and oxidative stress (OS) …
etiology is still unclear, although reactive oxygen species (ROS) and oxidative stress (OS) …
Autophagy/mitophagy in airway diseases: impact of oxidative stress on epithelial cells
GD Albano, AM Montalbano, R Gagliardo, M Profita - Biomolecules, 2023 - mdpi.com
Autophagy is the key process by which the cell degrades parts of itself within the lysosomes.
It maintains cell survival and homeostasis by removing molecules (particularly proteins) …
It maintains cell survival and homeostasis by removing molecules (particularly proteins) …
The coumarin-derivative esculetin protects against lipotoxicity in primary rat hepatocytes via attenuating jnk-mediated oxidative stress and attenuates free fatty acid …
M Xia, Z Wu, J Wang, M Buist-Homan, H Moshage - Antioxidants, 2023 - mdpi.com
Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …
Irisin protects against doxorubicin-induced cardiotoxicity by improving AMPK-Nrf2 dependent mitochondrial fusion and strengthening endogenous anti-oxidant …
C Zhuo, J Xin, W Huang, D Zhang, X Yan, R Li, H Li… - Toxicology, 2023 - Elsevier
Irisin, a new exercise-mediated myokine, plays an important role in cardiovascular diseases
by regulating cell energy metabolism. The induction of mitochondrial dysfunction and …
by regulating cell energy metabolism. The induction of mitochondrial dysfunction and …