Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an
atherosclerotic plaque. According to the 'response to injury'and 'vulnerable …

Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …

The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Vascular smooth muscle cells (SMCs), a major structural component of the vessel wall, not
only play a key role in maintaining vascular structure but also perform various functions …

Heterogeneity of embryological origins is a hallmark of vascular smooth muscle cells
(SMCs) and may influence the development of vascular disease. Differentiation of human …

Hematopoietic stem cells (HSCs) originate within the aortic-gonado-mesonephros (AGM)
region of the midgestation embryo, but the cell type responsible for their emergence is …

Smooth muscle cells (SMCs) play a key role in atherogenesis. However, mechanisms
regulating expansion and fate of pre-existing SMCs in atherosclerotic plaques remain poorly …

Rapid regeneration of smooth muscle after vascular injury is essential for maintaining
arterial function. The existence and putative roles of resident vascular stem cells (VSCs) in …

Conventional views of the tunica adventitia as a poorly organized layer of vessel wall
composed of fibroblasts, connective tissue, and perivascular nerves are undergoing …

Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the
endothelial cells (ECs) to regulate vascular stability and homeostasis. Here, we clarified the …