Protein crystallization has been known since 1840 and can prove to be straightforward but,
in most cases, it constitutes a real bottleneck. This stimulated the birth of the …

The ultimate goal of structural biology is to understand the structural basis of proteins in
cellular processes. In structural biology, the most critical issue is the availability of high …

Dynamic light scattering (DLS) analyses are routinely used in biology laboratories to detect
aggregates in macromolecular solutions, to determine the size of proteins, nucleic acids …

Focus a laser on dissolved particles and analyze the scattered light to reveal their size. This
well established principle is used in dynamic light scattering (DLS), or also called photon …

Oral insulin delivery could change the life of millions of diabetic patients as an effective, safe,
easy-to-use, and affordable alternative to insulin injections, known by an inherently thwarted …

Cytochrome c nitrite reductase (NrfA) catalyzes the reduction of nitrite to ammonium in the
dissimilatory nitrate reduction to ammonium (DNRA) pathway, a process that competes with …

In recent years, studies on psychrophilic lipases have become an emerging area of research
in the field of enzymology. The study described here focuses on the cold-adapted organic …

Sanitization of the cellular nucleotide pools from mutagenic base analogues is necessary for
the accuracy of transcription and replication of genetic material and plays a substantial role …

Every major biopharmaceutical company incorporates a protein crystallography unit that is
central to its structure-based drug discovery efforts. Yet these capabilities are rarely …

The identification of eight genes involved in inherited cobalamin (Cbl) disorders has
provided insight into the complexity of the vitamin B12 trafficking pathway. Detailed …