Current in vitro digestion systems for understanding food digestion in human upper gastrointestinal tract
Background Food digestion rate and location within the gastrointestinal (GI) tract are
important for human health. Ideally, food digestion studies should be performed in vivo but …
important for human health. Ideally, food digestion studies should be performed in vivo but …
Sensory influences on food intake control: moving beyond palatability
K McCrickerd, CG Forde - Obesity Reviews, 2016 - Wiley Online Library
The sensory experience of eating is an important determinant of food intake control, often
attributed to the positive hedonic response associated with certain sensory cues. However …
attributed to the positive hedonic response associated with certain sensory cues. However …
Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals
DJ McClements - Biotechnology advances, 2020 - Elsevier
Application of bioactive phytochemicals in foods, supplements, and pharmaceuticals is often
limited because of their poor solubility, stability, and bioavailability. Phytochemical oral …
limited because of their poor solubility, stability, and bioavailability. Phytochemical oral …
Re-evaluation of the mechanisms of dietary fibre and implications for macronutrient bioaccessibility, digestion and postprandial metabolism
The positive effects of dietary fibre on health are now widely recognised; however, our
understanding of the mechanisms involved in producing such benefits remains unclear …
understanding of the mechanisms involved in producing such benefits remains unclear …
Phytochemical delivery through nanocarriers: A review
In recent times, phytochemicals encapsulated or conjugated with nanocarriers for delivery to
the specific sites have gained considerable research interest. Phytochemicals are mostly …
the specific sites have gained considerable research interest. Phytochemicals are mostly …
[HTML][HTML] Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review
M Vertzoni, P Augustijns, M Grimm, M Koziolek… - European journal of …, 2019 - Elsevier
Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …
Food, gastrointestinal pH, and models of oral drug absorption
AY Abuhelwa, DB Williams, RN Upton… - European journal of …, 2017 - Elsevier
This article reviews the major physiological and physicochemical principles of the effect of
food and gastrointestinal (GI) pH on the absorption and bioavailability of oral drugs, and the …
food and gastrointestinal (GI) pH on the absorption and bioavailability of oral drugs, and the …
Starch digestibility in food matrix: a review
In this review, recent reports on in vitro starch hydrolysis kinetics are reviewed with regard to
the structural characteristics of starches. Factors such as starch granule morphology …
the structural characteristics of starches. Factors such as starch granule morphology …
In vitro models for the prediction of in vivo performance of oral dosage forms
ES Kostewicz, B Abrahamsson, M Brewster… - European Journal of …, 2014 - Elsevier
Accurate prediction of the in vivo biopharmaceutical performance of oral drug formulations is
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …
Physiological Parameters for Oral Delivery and in Vitro Testing
DM Mudie, GL Amidon, GE Amidon - Molecular pharmaceutics, 2010 - ACS Publications
Pharmaceutical solid oral dosage forms must undergo dissolution in the intestinal fluids of
the gastrointestinal tract before they can be absorbed and reach the systemic circulation …
the gastrointestinal tract before they can be absorbed and reach the systemic circulation …