Current in vitro digestion systems for understanding food digestion in human upper gastrointestinal tract

C Li, W Yu, P Wu, XD Chen - Trends in Food Science & Technology, 2020 - Elsevier
Background Food digestion rate and location within the gastrointestinal (GI) tract are
important for human health. Ideally, food digestion studies should be performed in vivo but …

Sensory influences on food intake control: moving beyond palatability

K McCrickerd, CG Forde - Obesity Reviews, 2016 - Wiley Online Library
The sensory experience of eating is an important determinant of food intake control, often
attributed to the positive hedonic response associated with certain sensory cues. However …

Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals

DJ McClements - Biotechnology advances, 2020 - Elsevier
Application of bioactive phytochemicals in foods, supplements, and pharmaceuticals is often
limited because of their poor solubility, stability, and bioavailability. Phytochemical oral …

Re-evaluation of the mechanisms of dietary fibre and implications for macronutrient bioaccessibility, digestion and postprandial metabolism

MML Grundy, CH Edwards, AR Mackie… - British Journal of …, 2016 - cambridge.org
The positive effects of dietary fibre on health are now widely recognised; however, our
understanding of the mechanisms involved in producing such benefits remains unclear …

Phytochemical delivery through nanocarriers: A review

R Ahmad, S Srivastava, S Ghosh, SK Khare - Colloids and Surfaces B …, 2021 - Elsevier
In recent times, phytochemicals encapsulated or conjugated with nanocarriers for delivery to
the specific sites have gained considerable research interest. Phytochemicals are mostly …

[HTML][HTML] Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review

M Vertzoni, P Augustijns, M Grimm, M Koziolek… - European journal of …, 2019 - Elsevier
Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

Food, gastrointestinal pH, and models of oral drug absorption

AY Abuhelwa, DB Williams, RN Upton… - European journal of …, 2017 - Elsevier
This article reviews the major physiological and physicochemical principles of the effect of
food and gastrointestinal (GI) pH on the absorption and bioavailability of oral drugs, and the …

Starch digestibility in food matrix: a review

J Singh, A Dartois, L Kaur - Trends in Food Science & Technology, 2010 - Elsevier
In this review, recent reports on in vitro starch hydrolysis kinetics are reviewed with regard to
the structural characteristics of starches. Factors such as starch granule morphology …

In vitro models for the prediction of in vivo performance of oral dosage forms

ES Kostewicz, B Abrahamsson, M Brewster… - European Journal of …, 2014 - Elsevier
Accurate prediction of the in vivo biopharmaceutical performance of oral drug formulations is
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …

Physiological Parameters for Oral Delivery and in Vitro Testing

DM Mudie, GL Amidon, GE Amidon - Molecular pharmaceutics, 2010 - ACS Publications
Pharmaceutical solid oral dosage forms must undergo dissolution in the intestinal fluids of
the gastrointestinal tract before they can be absorbed and reach the systemic circulation …