Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

Objective: Interest in candidate gene and candidate gene-by-environment interaction
hypotheses regarding major depressive disorder remains strong despite controversy …

The serotonin transporter (SERT) terminates serotonergic signalling through the sodium-and
chloride-dependent reuptake of neurotransmitter into presynaptic neurons. SERT is a target …

Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been
implicated in anxiety in humans and animal models and is the site of action of widely used …

Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …

The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …

Using radioligand binding assays, we determined the equilibrium dissociation constants
(KD's) for 37 antidepressants, three of their metabolites (desmethylcitalopram …

Serotonin (5-hydroxytryptophan, 5-HT) is a neurotransmitter synthesized in the raphe nuclei
of the brain stem and involved in the central control of food intake, sleep, and mood …

Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …