The application of mesoporous silica nanoparticles as a drug delivery vehicle in oral disease treatment

L Fang, H Zhou, L Cheng, Y Wang, F Liu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Mesoporous silica nanoparticles (MSNs) hold promise as safer and more effective
medication delivery vehicles for treating oral disorders. As the drug's delivery system, MSNs …

Mesoporous nanoparticles for diagnosis and treatment of liver cancer in the era of precise medicine

H Wu, MD Wang, JQ Zhu, ZL Li, WY Wang, LH Gu… - Pharmaceutics, 2022 - mdpi.com
Primary liver cancer is the seventh-most-common cancer worldwide and the fourth-leading
cause of cancer mortality. In the current era of precision medicine, the diagnosis and …

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

AK Meka, A Gopalakrishna, C Iriarte-Mesa… - Molecular …, 2023 - ACS Publications
Coenzyme Q10 is a potent antioxidant that plays an important role in the maintenance of
various biochemical pathways of the body and has a wide range of therapeutic applications …

Biotin-modified mesoporous silica nanoparticles as a delivery system for quercetin and gallic acid for bacterial biofilm eradication

S Hua, Y Wang, Y Li, S Liu, J Wen, LJ Walsh… - Journal of Materials …, 2024 - Springer
The effective management of biofilm-associated infections remains a pressing concern in
clinical practice, necessitating the development of efficient eradication strategies. This study …

Understanding fenofibrate release from bare and modified mesoporous silica nanoparticles

G Figari, JLM Gonçalves, HP Diogo, M Dionísio… - Pharmaceutics, 2023 - mdpi.com
To investigate the impact of the surface functionalization of mesoporous silica nanoparticle
(MSN) carriers in the physical state, molecular mobility and the release of Fenofibrate (FNB) …

Mesoporous silica nanoparticles co-loaded with lysozyme and vancomycin for synergistic antimicrobial action

N Namdar, B Nayeri Fasaei, P Shariati… - Scientific Reports, 2024 - nature.com
Nanotechnology offers a novel strategy for enhancing the susceptibility of pathogens
resistant to traditional antibiotics. Another effective strategy is combination therapy, where …

Evidence of Strong Guest–Host Interactions in Simvastatin Loaded in Mesoporous Silica MCM-41

T Cordeiro, I Matos, F Danède, JC Sotomayor… - Pharmaceutics, 2023 - mdpi.com
A rational design of drug delivery systems requires in-depth knowledge not only of the drug
itself, in terms of physical state and molecular mobility, but also of how it is distributed among …

Sortase A inhibitor protein nanoparticle formulations demonstrate antibacterial synergy when combined with antimicrobial peptides

S Alharthi, A Popat, ZM Ziora, PM Moyle - Molecules, 2023 - mdpi.com
Sortase A (SrtA) is an enzyme which attaches proteins, including virulence factors, to
bacterial cell walls. It is a potential target for developing anti-virulence agents against …

CD133-targeted multifunctional nanomicelles for dual-modality imaging and synergistic high-intensity focus ultrasound (HIFU) ablation on pancreatic cancer in nude …

Y Yao, Y Zheng, M Wu, Y Gao, Q Yu, M Liu… - Journal of Materials …, 2024 - pubs.rsc.org
Pancreatic cancer is an aggressive and highly fatal malignant tumor. Recent studies have
shown that cancer stem cells (CSCs) play an important role in resisting current therapeutic …

Can bee propolis help us fight against methicillin-resistant Staphylococcus aureus (MRSA)?

N Ripari, M Beatriz Toti… - RPS Pharmacy and …, 2022 - academic.oup.com
Abstract Objectives Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-
resistant pathogen in nosocomial infections. Since the 1950s, MRSA has acquired several …