The rapid advancement of nanotechnology has raised the possibility of using engineered
nanoparticles that interact within biological environments for treatment of diseases …

Particulate carrier systems are promising drug delivery vehicles for subunit vaccination as
they can enhance and direct the type of T cell response. In order to develop vaccines with …

The development of novel immune adjuvants is emerging as a significant area of vaccine
delivery based on the continued necessity to amplify immune responses to a wide array of …

Injectable biodegradable and biocompatible copolymers of lactic and glycolic acid (PLGA)
are an important advanced delivery system for week-to-month controlled release of …

Biodegradable nano/microparticles of poly (d, l-lactide-co-glycolide)(PLGA) and PLGA-
based polymers are widely explored as carriers for controlled delivery of macromolecular …

With very few adjuvants currently being used in marketed human vaccines, a critical need
exists for novel immunopotentiators and delivery vehicles capable of eliciting humoral …

The use of particulate carriers holds great promise for the development of effective and
affordable recombinant vaccines. Rational development requires a detailed understanding …

Developing efficient and safe adjuvants for use in human vaccines remains both a challenge
and a necessity. Past approaches have been largely empirical and generally used a single …

Despite great advances in the field of vaccination, there are still needs for novel and
effective vaccines because still no effective vaccines have been produced for some …

Adjuvant design has historically had a touch of alchemy at its heart due to its reliance on the
complex biology of innate immune activation. However, a new mechanistic understanding of …