Chemometrics

B Lavine, J Workman - Analytical chemistry, 2008 - ACS Publications
This review, the seventeenth of this series and the fifteenth with the title of Chemometrics,
covers the most significant developments in the field from January 2006 through December …

Chemometric methods in analytical spectroscopy technology

Y Huang - Chemometric Methods in Analytical Spectroscopy …, 2022 - Springer
In recent decades, with the rapid development of artificial intelligence, data mining, and
cloud computing, new chemometric methods have sprung up and become one of the fastest …

Data reconciliation of concentration estimates from mid‐infrared and dielectric spectral measurements for improved on‐line monitoring of bioprocesses

M Dabros, M Amrhein, D Bonvin… - Biotechnology …, 2009 - Wiley Online Library
Real‐time data reconciliation of concentration estimates of process analytes and biomass in
microbial fermentations is investigated. A Fourier‐transform mid‐infrared spectrometer …

Potential of mid-infrared spectroscopy for on-line monitoring of mammalian cell culture medium components

R Foley, S Hennessy, IW Marison - Applied Spectroscopy, 2012 - journals.sagepub.com
This study proposed a methodology to evaluate the potential of midinfrared (MIR)
spectroscopy as a process analytical technology (PAT) tool for in situ (in-line) monitoring of …

Framework for explicit drift correction in multivariate calibration models

P Gujral, M Amrhein, BM Wise… - Journal of …, 2010 - Wiley Online Library
Latent‐variable calibrations using principal component regression and partial least‐squares
regression are often compromised by drift such as systematic disturbances and offsets. This …

Drift correction in multivariate calibration models using on-line reference measurements

P Gujral, M Amrhein, D Bonvin - Analytica chimica acta, 2009 - Elsevier
On-line measurements from first-order instruments such as spectrometers may be
compromised by instrumental, process and operational drifts that are not seen during off-line …

Calibration Transfer Methods

Y Huang - Chemometric Methods in Analytical Spectroscopy …, 2022 - Springer
A situation is often encountered in the process of spectral analysis that when the model
established on one spectrometer (master, primary, and parent instrument) is used on …

Cloning instruments, model maintenance and calibration transfer

Most literature on the application of Non-Destructive Spectral Sensors (NDSS) reports proofs
of concept limited to model calculation (calibration) and its application on a so-called …

Cost-efficient strategies for building, transferring, and maintaining multivariate calibration models for spectroscopic sensors

V Fonseca Diaz - 2022 - lirias.kuleuven.be
The process of quality control for the inspection of products in industries requires methods
that quantify the concentration of chemical constituents before products are distributed to …

The development and application of mid-infrared spectroscopy as a process analytical technology (PAT) tool for cell culture applications

R Foley - 2013 - doras.dcu.ie
The objective of this thesis was to investigate the use of mid-infrared spectroscopy (MIR) as
a PAT tool in bioprocessing. This was achieved through the development of chemometric …