Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Infiltration to infection: key virulence players of Helicobacter pylori pathogenicity

A Bhattacharjee, OS Sahoo, A Sarkar, S Bhattacharya… - Infection, 2024 - Springer
Purpose This study aims to comprehensively review the multifaceted factors underlying the
successful colonization and infection process of Helicobacter pylori (H. pylori), a prominent …

Association of Helicobacter pylori babA2 gene and gastric cancer risk: a meta-analysis

MA Kpoghomou, J Wang, T Wang, G Jin - BMC cancer, 2020 - Springer
Abstract Background The association of Helicobacter pylori (H. pylori) babA2 gene with
gastric cancer (GC) was reported by several studies, but results were inconsistent. This meta …

[HTML][HTML] Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer

MY Chen, CY He, X Meng, Y Yuan - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the association between babA2 gene and peptic ulcer disease (PUD)
and gastric cancer (GC) in Helicobacter pylori-infected populations. METHODS: We …

Clinical relevance of Helicobacter pylori virulence factors in Iranian patients with gastrointestinal diseases

N Bagheri, F Azadegan-Dehkordi… - Microbial …, 2016 - Elsevier
Helicobacter pylori (H. pylori) usually colonizes the gastric mucosa of more than 50% of the
human population, causing an infection that may appear in early childhood and can persist …

IL1 Receptor Antagonist Gene IL1-RN Variable Number of Tandem Repeats Polymorphism and Cancer Risk: A Literature Review and Meta-Analysis

Y Zhang, C Liu, H Peng, J Zhang, Q Feng - 2012 - journals.plos.org
IL1 receptor antagonist (IL1RA) and IL1beta (IL1β), members of the pro-inflammatory
cytokine interleukin-1 (IL1) family, play a potential role against infection and in the …

Genetic variants in gastric cancer: risks and clinical implications

CO Gigek, DQ Calcagno, LT Rasmussen… - … and molecular pathology, 2017 - Elsevier
Cancer is a multifactorial disease that involves many molecular alterations. Gastric cancer
(GC) is the third leading cause of cancer death worldwide. GC is a highly heterogeneous …

Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer

K Dadashzadeh, MP Peppelenbosch… - Canadian Journal of …, 2017 - Wiley Online Library
Background. Although the causal relationship between Helicobacter pylori infection and the
development of gastric cancer is firmly established, the exact nature of the pathogenicity …

Gene polymorphism of interleukin 1 and 8 in chronic gastritis patients infected withHelicobacter pylori

A Caleman, LT Rasmussen, RW Labio… - Journal of Venomous …, 2014 - SciELO Brasil
Background: Epidemiological investigations have indicated that Helicobacter pylori induces
inflammation in the gastric mucosa regulated by several interleukins. The genes IL1B and …

Polymorphisms in interleukin-1B (IL-1B) and interleukin 1 receptor antagonist (IL-1RN) genes associate with gastric cancer risk in the Chinese population

BS He, YQ Pan, YF Xu, C Zhu, LL Qu… - Digestive diseases and …, 2011 - Springer
Background Gastric cancer is one of the most common malignancies afflicting the Chinese
population. Polymorphisms in interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL …