Background Norcantharidin (NCTD) has a certain degree of hydrophilicity and poor
lipophilicity, and has some side-effects, including short t1/2, vascular irritation, cardiotoxicity …

Docetaxel (DTX) has become one of the most important cytotoxic drugs to treat cancer;
nevertheless, its poor hydrophilicity and non-specific distribution of DTX lead to detrimental …

Tranexamic acid (TXA) is an anti-fibrinolysis agent widely used in postoperative blood loss
management. As a highly water-soluble drug, TXA is suffering from rapid clearance from the …

Vincristine (VCR), as a cytotoxic drug, is used clinically to treat acute lymphatic leukemia
and breast cancer, and commonly used clinically as vincristine sulfate (VCRS). However, its …

Purpose To develop once-a-month long acting semaglutide injectable, its manufacturing
process was optimized. The final product to be selected based on improved …

Background: Linagliptin (LNG) exhibits poor bioavailability and numerous side effects,
significantly limiting its use. Transdermal drug delivery systems (TDDS) offer a potential …

This experiment was done to study the zeolite molecular sieve as a drug-binding effector,
the non-antibiotic drug potassium diformate uniformly disperse in the internal aqueous …

Microspheres, a potential drug delivery approach, has opened a new era for attaining
versatile release patterns needed. By optimizing the formulation variables, they can be …