Molecular biomarkers in cancer
VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
Large-scale single-cell and bulk sequencing analyses reveal the prognostic value and immune aspects of CD147 in pan-cancer
CD147 plays an important role in promoting tumor proliferation and inhibiting cancer cell
apoptosis in the tumor microenvironment. However, the mechanisms by which CD147 is …
apoptosis in the tumor microenvironment. However, the mechanisms by which CD147 is …
Intrinsic molecular subtypes of metastatic castration-resistant prostate cancer
Purpose: Although numerous biology-driven subtypes have been described previously in
metastatic castration-resistant prostate cancer (mCRPC), unsupervised molecular subtyping …
metastatic castration-resistant prostate cancer (mCRPC), unsupervised molecular subtyping …
Identification of phenocopies improves prediction of targeted therapy response over DNA mutations alone
DNA mutations in specific genes can confer preferential benefit from drugs targeting those
genes. However, other molecular perturbations can “phenocopy” pathogenic mutations, but …
genes. However, other molecular perturbations can “phenocopy” pathogenic mutations, but …
Pan-cancer and single-cell analysis reveal the prognostic value and immune response of NQO1
L Shen, S Jiang, Y Yang, H Yang, Y Fang… - Frontiers in Cell and …, 2023 - frontiersin.org
Background: Overexpression of the NAD (P) H: Quinone Oxidoreductase 1 (NQOI) gene has
been linked with tumor progression, aggressiveness, drug resistance, and poor patient …
been linked with tumor progression, aggressiveness, drug resistance, and poor patient …
[HTML][HTML] Pan-cancer analysis of the immune aspects and prognostic value of NCAPG2
H Feng, N Chen, H Li, Z Zheng, H Li, H Quan, X Jin… - Heliyon, 2023 - cell.com
NCAPG2 has been reported to be associated with tumorigenesis in various types of cancer.
However, data on the pathological mechanisms of NCAPG2 in pan-cancers remain lacking …
However, data on the pathological mechanisms of NCAPG2 in pan-cancers remain lacking …
[PDF][PDF] Molecular Biomarkers in Cancer. Biomolecules 2022, 12, 1021
VK Sarhadi, G Armengol - 2022 - helda.helsinki.fi
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
Deep pan-cancer analysis and multi-omics evidence reveal that ALG3 inhibits CD8+ T cell infiltration by suppressing chemokine secretion and is associated with 5 …
Z Wu, R Su, Y Dai, X Wu, H Wu, X Wang… - Computers in Biology …, 2024 - Elsevier
Abstract Background α-1, 3-mannosyltransferase (ALG3) holds significance as a key
member within the mannosyltransferase family. Nevertheless, the exact function of ALG3 in …
member within the mannosyltransferase family. Nevertheless, the exact function of ALG3 in …
The role of FERMT2 in the tumor microenvironment and immunotherapy in pan-cancer using comprehensive single-cell and bulk sequencing
G Wu, C He, G Che, Z Zhou, B Chen, H Wu, J Chen… - Heliyon, 2024 - cell.com
FERMT2 has been identified as a participant in integrin-linked kinase signaling pathways,
influencing epithelial-mesenchymal transition and thereby affecting tumor initiation …
influencing epithelial-mesenchymal transition and thereby affecting tumor initiation …
[HTML][HTML] Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospective Study
Background: This multicenter and retrospective study investigated the additive value of
tumor morphologic features derived from the functional tumor volume (FTV) tumor mask at …
tumor morphologic features derived from the functional tumor volume (FTV) tumor mask at …