The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease
Transforming growth factor-βs (TGF-βs) and bone morphometric proteins (BMPs) belong to
the TGF-β superfamily and perform essential functions during osteoblast and chondrocyte …
the TGF-β superfamily and perform essential functions during osteoblast and chondrocyte …
YAP/TAZ in bone and cartilage biology
M Zarka, E Haÿ, M Cohen-Solal - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
YAP and TAZ were initially described as the main regulators of organ growth during
development and more recently implicated in bone biology. YAP and TAZ are regulated by …
development and more recently implicated in bone biology. YAP and TAZ are regulated by …
Functional micro-RNA drugs acting as a fate manipulator in the regulation of osteoblastic death
Z Cai, F Liu, Y Li, L Bai, M Feng, S Li, W Ma, S Shi - Nanoscale, 2023 - pubs.rsc.org
Bone loss is prevalent in clinical pathological phenomena such as osteoporosis, which is
characterized by decreased osteoblast function and number, increased osteoclast activity …
characterized by decreased osteoblast function and number, increased osteoclast activity …
[HTML][HTML] Shaping the bone through iron and iron-related proteins
MG Ledesma-Colunga, H Weidner, MV Spasic… - Seminars in …, 2021 - Elsevier
Well-controlled iron levels are indispensable for health. Iron deficiency is the most common
cause of anemia, whereas iron overload, either hereditary or secondary due to disorders of …
cause of anemia, whereas iron overload, either hereditary or secondary due to disorders of …
Structural characterization and osteogenic differentiation-promoting activity of polysaccharide purified from Chroogomphus rutilus
Y Zhou, L Li, Z Sun, R Liu, Y Zhu, J Yi, Y Li, M Hu… - Carbohydrate …, 2024 - Elsevier
Chroogomphus rutilus (CR) possesses anti-inflammatory, antioxidant, and hypoglycemic
properties. However, studies are yet to evaluate the anti-osteoporotic activity of the fungi and …
properties. However, studies are yet to evaluate the anti-osteoporotic activity of the fungi and …
[HTML][HTML] Total flavonoids of rhizoma drynariae ameliorates bone formation and mineralization in BMP-Smad signaling pathway induced large tibial defect rats
W Sun, M Li, Y Zhang, Y Huang, Q Zhan, Y Ren… - Biomedicine & …, 2021 - Elsevier
Osteogenesis and angiogenesis acts as an essential role in repairing large tibial defects
(LTDs). Total flavonoids of rhizoma drynariae (TFRD), a traditional Chinese medicinal herb …
(LTDs). Total flavonoids of rhizoma drynariae (TFRD), a traditional Chinese medicinal herb …
Fluchloralin induces developmental toxicity in heart, liver, and nervous system during early zebrafish embryogenesis
The zebrafish is a prominent vertebrate model popularly used for toxicity testing because of
its rapid development and transparent embryos. Fluchloralin, a dinitroaniline herbicide used …
its rapid development and transparent embryos. Fluchloralin, a dinitroaniline herbicide used …
Enhanced osteogenic differentiation of human bone–derived mesenchymal stem cells in 3‐dimensional printed porous titanium scaffolds by static magnetic field …
Y He, L Yu, J Liu, Y Li, Y Wu, Z Huang, D Wu… - The FASEB …, 2019 - Wiley Online Library
The reconstruction of large bone defects remains a significant challenge for orthopedists.
Three‐dimensional–printed (3DP) scaffold is considered a promising repair material. Static …
Three‐dimensional–printed (3DP) scaffold is considered a promising repair material. Static …
mRNA-miRNA-lncRNA regulatory network in nonalcoholic fatty liver disease
M Matboli, SH Gadallah, WM Rashed… - International journal of …, 2021 - mdpi.com
Aim: we aimed to construct a bioinformatics-based co-regulatory network of mRNAs and non
coding RNAs (ncRNAs), which is implicated in the pathogenesis of non-alcoholic fatty liver …
coding RNAs (ncRNAs), which is implicated in the pathogenesis of non-alcoholic fatty liver …
Liraglutide exerts a bone‑protective effect in ovariectomized rats with streptozotocin‑induced diabetes by inhibiting osteoclastogenesis
B Wen, L Zhao, H Zhao, X Wang - Experimental and …, 2018 - spandidos-publications.com
Liraglutide, a glucagon‑like peptide‑1 receptor agonist, is an anti‑diabetic medicine
associated with a reduced risk of fracture in diabetic patients. In the present study, rats with …
associated with a reduced risk of fracture in diabetic patients. In the present study, rats with …