Aggrescan4D: A comprehensive tool for pH‐dependent analysis and engineering of protein aggregation propensity
Abstract Aggrescan4D (A4D) is an advanced computational tool designed for predicting
protein aggregation, leveraging structural information and the influence of pH. Building upon …
protein aggregation, leveraging structural information and the influence of pH. Building upon …
Exploring protein functions from structural flexibility using CABS‐flex modeling
Understanding protein function often necessitates characterizing the flexibility of protein
structures. However, simulating protein flexibility poses significant challenges due to the …
structures. However, simulating protein flexibility poses significant challenges due to the …
A3D Model Organism Database (A3D-MODB): a database for proteome aggregation predictions in model organisms
AE Badaczewska-Dawid, A Kuriata… - Nucleic Acids …, 2024 - academic.oup.com
Protein aggregation has been associated with aging and different pathologies and
represents a bottleneck in the industrial production of biotherapeutics. Numerous past …
represents a bottleneck in the industrial production of biotherapeutics. Numerous past …
[HTML][HTML] Bioengineered self-assembled nanofibrils for high-affinity SARS-CoV-2 capture and neutralization
M Behbahanipour, S Navarro, O Bárcenas… - Journal of colloid and …, 2024 - Elsevier
The recent coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spurred intense research efforts to …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spurred intense research efforts to …
A Reversible Spherical Geometric Conversion of Protein Backbone Structure Coordinate Matrix to Three Independent Vectors of ρ, θ and φ
W Li - 2024 - preprints.org
Due to the vast conformational space proteins can adopt, accurate and efficient prediction of
protein structure remains still a challenging task, coupled with the intricacies of interatomic …
protein structure remains still a challenging task, coupled with the intricacies of interatomic …
Advanced computational approaches to understand protein aggregation
D Ghosh, A Biswas, M Radhakrishna - Biophysics Reviews, 2024 - pubs.aip.org
Protein aggregation is a widespread phenomenon implicated in debilitating diseases like
Alzheimer's, Parkinson's, and cataracts, presenting complex hurdles for the field of …
Alzheimer's, Parkinson's, and cataracts, presenting complex hurdles for the field of …
Deciphering the modulatory role of mutations in protein aggregation through in silico methods
A substantial portion of the cellular homeostasis network is dedicated to managing the
consequences of protein aggregation, a process that cannot be avoided. In recent decades …
consequences of protein aggregation, a process that cannot be avoided. In recent decades …