Toposeg: Topology-aware nuclear instance segmentation

H He, J Wang, P Wei, F Xu, X Ji… - Proceedings of the …, 2023 - openaccess.thecvf.com
Nuclear instance segmentation has been critical for pathology image analysis in medical
science, eg, cancer diagnosis. Current methods typically adopt pixel-wise optimization for …

Topology-aware uncertainty for image segmentation

S Gupta, Y Zhang, X Hu… - Advances in Neural …, 2024 - proceedings.neurips.cc
Segmentation of curvilinear structures such as vasculature and road networks is challenging
due to relatively weak signals and complex geometry/topology. To facilitate and accelerate …

Calibrating uncertainty for semi-supervised crowd counting

C Li, X Hu, S Abousamra… - 2023 IEEE/CVF …, 2023 - ieeexplore.ieee.org
Semi-supervised crowd counting is an important yet challenging task. A popular approach is
to iteratively generate pseudo-labels for unlabeled data and add them to the training set …

Semi-supervised segmentation of histopathology images with noise-aware topological consistency

M Xu, X Hu, S Gupta, S Abousamra, C Chen - European Conference on …, 2025 - Springer
In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial
for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we …

Deep Closing: Enhancing Topological Connectivity in Medical Tubular Segmentation

Q Wu, Y Chen, W Liu, X Yue… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Accurately segmenting tubular structures, such as blood vessels or nerves, holds significant
clinical implications across various medical applications. However, existing methods often …

TopoSemiSeg: Enforcing Topological Consistency for Semi-Supervised Segmentation of Histopathology Images

M Xu, X Hu, S Gupta, S Abousamra, C Chen - arXiv preprint arXiv …, 2023 - arxiv.org
In computational pathology, segmenting densely distributed objects like glands and nuclei is
crucial for downstream analysis. To alleviate the burden of obtaining pixel-wise annotations …

TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Model

M Xu, S Gupta, X Hu, C Li, S Abousamra… - arXiv preprint arXiv …, 2024 - arxiv.org
Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides
critical insights into tissue structure and pathology. The synthetic generation of cell topology …

Scale-Free Image Keypoints Using Differentiable Persistent Homology

G Barbarani, F Vaccarino, G Trivigno, M Guerra… - arXiv preprint arXiv …, 2024 - arxiv.org
In computer vision, keypoint detection is a fundamental task, with applications spanning from
robotics to image retrieval; however, existing learning-based methods suffer from scale …

Neurovascular Segmentation in sOCT with Deep Learning and Synthetic Training Data

E Chollet, Y Balbastre, C Mauri, C Magnain… - arXiv preprint arXiv …, 2024 - arxiv.org
Microvascular anatomy is known to be involved in various neurological disorders. However,
understanding these disorders is hindered by the lack of imaging modalities capable of …

High-throughput analysis of dendrite and axonal arbors reveals transcriptomic correlates of neuroanatomy

O Gliko, M Mallory, R Dalley, R Gala, J Gornet… - Nature …, 2024 - nature.com
Neuronal anatomy is central to the organization and function of brain cell types. However,
anatomical variability within apparently homogeneous populations of cells can obscure such …