Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several
antineoplastics. It can lead to detrimental dose reductions and discontinuation of treatment …

Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

PURPOSE To update the ASCO guideline on the recommended prevention and treatment
approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in …

Mast cells are best recognized for their role in allergy and anaphylaxis, but increasing
evidence supports their role in neurogenic inflammation leading to pain and itch. Mast cells …

Chemotherapy-induced peripheral neuropathic pain (CIPNP)—a severe adverse effect
observed in up to 80% of patients during treatment with antineoplastic drugs—limits the …

Simple Summary Vincristine is a vinca alkaloid naturally occurring in Catharanthus roseus. It
belongs to antimitotic compounds, which arrest the cell cycle via disrupting microtubule …

One of the most neglected aspects of chemotherapy are changes, and possible
consequences of these changes, that occur in normal somatic cells. In this review, we …

Bortezomib, a first-generation proteasome inhibitor widely used in chemotherapy for
hematologic malignancy, has effective anti-cancer activity but often causes severe …

Chemotherapy-induced peripheral neuropathy (CIPN) and associated neuropathic pain are
challenging complications of cancer treatment. Many of the major classes of …

Chemotherapy‐induced peripheral neuropathy (CIPN) is a serious adverse side effect of
many chemotherapeutic agents, affecting> 60% of patients with cancer. Moreover, CIPN …