As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread
globally, it became evident that the SARS-CoV-2 virus infects multiple organs including the …

Mechanotransduction refers to the ability of cells to sense mechanical stimuli and convert
them into biochemical signals. In this context, the key players are focal adhesions (FAs) …

The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as
well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT1 …

The initiation or progression of periodontitis might involve a local renin-angiotensin system
(RAS) in periodontal tissue. The aim of this study was to further characterize the local RAS in …

In November 2019 the first cases of a novel acute respiratory syndrome has been reported
in Wuhan province, China. Soon after, in January 2020 the World Health Organization …

Rheumatoid arthritis is an autoimmune disease that affects joints, leading to swelling,
inflammation, and dysfunction in the joints. Recently, research efforts have been focused on …

One major cause of cardiac mortality is heart disease caused by hypertension. The
formation of cyclic adenosine monophosphate (cAMP) is inhibited by calcium-sensitive …

G protein-coupled receptors (GPCRs) are involved in essentially all physiological processes
in mammals. The classical GPCR signal transduction mechanism occurs by coupling to G …

The angiotensin type 2 (AT2) receptor and the bradykinin type 2 (B2) receptor are G protein-
coupled receptors (GPCRs) that have major roles in the cardiovascular system. The two …

The regulation of the kallikrein-kinin system is an important mechanism controlling
vasodilation and promoting inflammation. We aimed to investigate the role of Toll-like …