Simple Summary By studying the cancer-inducing ability of polyomaviruses, several
milestones in cancer research crucially contributing to our current understanding of, eg, the …

Human tumor viruses cause various human cancers that account for at least 15% of the
global cancer burden. Among the currently identified human tumor viruses, two are small …

Merkel cell carcinoma (MCC) is an extremely rare cutaneous neuroendocrine cancer, with
an incidence approximately 40 times lower than that of malignant melanoma; however, its …

Approximately 20% of human cancers are associated with virus infection. DNA tumor viruses
can induce tumor formation in host cells by disrupting the cell's DNA replication and repair …

Lung cancer stands as one of the most lethal diseases and is the foremost cause of cancer-
related mortalities worldwide. The pathophysiology of lung cancer is multifaceted, and it …

Simple Summary Efforts have been directed toward exploring the pathophysiology
underlying virus-positive and virus-negative Merkel cell carcinoma. An increasing amount of …

Simple Summary Merkel cell polyomavirus is a widespread pathogen, strongly associated
with the highly aggressive Merkel cell carcinoma. In this review paper we aim to examine a …

The large T antigen (LT) of the Merkel cell polyomavirus (MCPyV) is crucial for Merkel cell
carcinoma (MCC), a rare but very aggressive form of neuroendocrine skin cancer. The …

Despite recent advances in prevention, detection and treatment, oral squamous cell
carcinoma (OSCC) remains a global health concern, strongly associated with environmental …

Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma
thought to arise via either viral (Merkel cell polyomavirus) or ultraviolet-associated pathways …