Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …

Many patients with inflammatory bowel disease (IBD) have persistent symptoms and
disease activity despite the best available medical or surgical treatments. These patients are …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Spondyloarthritis (SpA) encompasses a heterogeneous group of chronic inflammatory
diseases that can affect both axial and peripheral joints, tendons and entheses. Among the …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

A growing number of patients with Crohn's disease and ulcerative colitis have disease that is
refractory to multiple advanced therapies, have undergone multiple surgeries and require …

Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

The term “immune-mediated inflammatory diseases (IMIDs)” refers to several inflammatory
pathologies of multifactorial etiology and involving either simultaneously or sequentially …

Artificial intelligence (AI) refers to computer-based methodologies which use data to teach a
computer to solve pre-defined tasks; these methods can be applied to identify patterns in …

Ulcerative colitis (UC) is a chronic and progressive inflammatory disorder that affects the
colon. The advent of advanced therapies such as biologic agents and small molecules has …