Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Chagas disease, caused by the Trypanosoma cruzi parasitic protozoan, is a neglected
tropical disease (NTD) of significant incidence in Latin America. Transmission to humans …

The drugs available for Chagas disease treatment are toxic and ineffective. We studied the
in vivo activity of a new drug, lychnopholide (LYC). LYC was loaded in nanocapsules (NC) …

Chagas disease is a neglected parasitic disease caused by the protozoan Trypanosoma
cruzi. New antitrypanosomal options are desirable to prevent complications, including a high …

Purpose: Mesoporous silica nanoparticles (MSNs) have drawn substantial interest as drug
nanocarriers for breast cancer therapy. Nevertheless, because of the hydrophilic surfaces …

The etiological treatment of Chagas disease remains neglected. The compounds available
show several limitations, mainly during the chronic phase. Lychnopholide encapsulated in …

Chagas disease (CD) remains neglected and causes high morbidity and mortality. The great
difficulty is the lack of effective treatment. The current drugs cause side effects and have …

Chagas disease remains neglected, and current chemotherapeutics present severe
limitations. Lychnopholide (LYC) at low doses loaded in polymeric poly (d, l-lactide)-block …

Background: The current drugs for Chagas disease treatment present several
limitationsMethods: The sesquiterpene lactone goyazensolide (GZL) was evaluated …

The films based on methylcellulose with biodegradable and antioxidant activity incorporated
with nano capsule suspension containing F. angulata essential oil were developed. Oil …