The principal source of vitamin D in humans is its biosynthesis in the skin through a
chemical reaction dependent on sun exposure. In lesser amounts, the vitamin can be …

1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D deficiency is typically caused by inadequate cutaneous synthesis secondary to
decreased exposure to sunlight. Serum levels of 25-hydroxyvitamin D l< 20 ng/ml are …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Cardiac dysfunction in CKD is characterized by aberrant cardiac remodeling with
hypertrophy and fibrosis. CKD is a state of severe systemic Klotho deficiency, and …

Vitamin D deficiency has been linked to many human diseases such as Alzheimer's disease
(AD), Parkinson's disease (PD), multiple sclerosis (MS), hypertension and cardiovascular …

In the last decade, an increasing awareness was directed to the role of Vitamin D in non-
skeletal and preventive roles for chronic diseases. Vitamin D is an essential hormone in …

Aims The present study investigated whether or not calcitriol, an active form of vitamin D,
protects against renovascular dysfunction in hypertension and, if so, whether or not such …

Vitamin D deficiency, prevalent in 30–50% of adults in developed countries, is largely due to
inadequate cutaneous production that results from decreased exposure to sunlight, and to a …

Vitamin D is a hormone that maintains healthy cells. It functions by regulating the low resting
levels of cell signalling components such as Ca2+ and reactive oxygen species (ROS). Its …