Prefrontal cortex executive processes affected by stress in health and disease

M Girotti, SM Adler, SE Bulin, EA Fucich… - Progress in Neuro …, 2018 - Elsevier
Prefrontal cortical executive functions comprise a number of cognitive capabilities necessary
for goal directed behavior and adaptation to a changing environment. Executive dysfunction …

Social defeat stress: Mechanisms underlying the increase in rewarding effects of drugs of abuse

S Montagud‐Romero… - European Journal of …, 2018 - Wiley Online Library
Social interaction is known to be the main source of stress in human beings, which explains
the translational importance of this research in animals. Evidence reported over the last …

[HTML][HTML] Intermittent voluntary wheel running promotes resilience to the negative consequences of repeated social defeat in mice

C Calpe-López, MA Martínez-Caballero… - Physiology & …, 2022 - Elsevier
A novel approach to reduce the incidence of substance use disorders is to promote
resilience to stress using environmental resources such as physical exercise. In the present …

Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

L Caputo, MD Reguilon, J Mińarro, V De Feo… - Molecules, 2018 - mdpi.com
Many vegetable extracts, essential oils, and their main constituents are active on the Central
Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers …

[HTML][HTML] Resilience to social defeat stress in adolescent male mice

MD Reguilón, R Ballestín, J Miñarro… - Progress in Neuro …, 2022 - Elsevier
Adverse social experiences during adolescence are associated with the appearance of
mental illness in adulthood. Social defeat (SD) is an ethologically valid murine model to …

Oxytocin prevents the increase of cocaine-related responses produced by social defeat

C Ferrer-Pérez, A Castro-Zavala, MÁ Luján… - …, 2019 - Elsevier
The neuropeptide oxytocin (OXT) plays a critical role in the regulation of social and
emotional behaviors. OXT plays a role in stress response and in drug reward, but to date no …

Social stress during adolescence activates long-term microglia inflammation insult in reward processing nuclei

M Rodríguez-Arias, S Montagud-Romero… - PLoS …, 2018 - journals.plos.org
The experience of social stress during adolescence is associated with higher vulnerability to
drug use. Increases in the acquisition of cocaine self-administration, in the escalation of …

Voluntary wheel running protects against the increase in ethanol consumption induced by social stress in mice

MD Reguilón, C Ferrer-Pérez, R Ballestín… - Drug and Alcohol …, 2020 - Elsevier
Previous studies have shown that exposure to social defeat (SD), a model of social stress,
produces a long-term increase in the consumption of ethanol, most likely through an …

[HTML][HTML] Decreased kynurenine pathway potentiate resilience to social defeat effect on cocaine reward

P Giménez-Gómez, R Ballestín… - …, 2021 - Elsevier
The kynurenine (KYN) pathway of tryptophan (TRP) degradation is activated by stress and
inflammatory factors. It is now well established that social stress induces the activation of the …

[HTML][HTML] Oleoylethanolamide attenuates the stress-mediated potentiation of rewarding properties of cocaine associated with an increased TLR4 proinflammatory …

M González-Portilla, M Moya… - Progress in Neuro …, 2023 - Elsevier
The lipid-derived messenger oleoylethanolamide (OEA) has been involved in multiple
physiological functions including metabolism and the immune response. More recently, OEA …