Measuring DNA modifications with the comet assay: a compendium of protocols
A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
An overview of comet assay application for detecting DNA damage in aquatic animals
This review discusses several research studies that employed comet assay to evaluate the
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …
Catalase‐Mimetic Artificial Biocatalysts with Ru Catalytic Centers for ROS Elimination and Stem‐Cell Protection
Y Sun, S Mu, Z Xing, J Guo, Z Wu, F Yu… - Advanced …, 2022 - Wiley Online Library
Exploring high‐efficiency reactive oxygen species (ROS)‐elimination materials is of great
importance for combating oxidative stress in diverse diseases, especially stem‐cell‐based …
importance for combating oxidative stress in diverse diseases, especially stem‐cell‐based …
Genotoxicity of particles from grinded plastic items in Caco-2 and HepG2 cells
M Roursgaard, M Hezareh Rothmann… - Frontiers in Public …, 2022 - frontiersin.org
Large plastic litters degrade in the environment to micro-and nanoplastics, which may then
enter the food chain and lead to human exposure by ingestion. The present study explored …
enter the food chain and lead to human exposure by ingestion. The present study explored …
DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death
The comet assay or single cell gel electrophoresis, is the most common method used to
measure strand breaks and a variety of other DNA lesions in human populations. To …
measure strand breaks and a variety of other DNA lesions in human populations. To …
[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
Stress driven discovery of natural products from actinobacteria with anti-oxidant and cytotoxic activities including docking and admet properties
SS Hassan, I Muhammad, SQ Abbas… - International Journal of …, 2021 - mdpi.com
Elicitation through abiotic stress, including chemical elicitors like heavy metals, is a new
technique for drug discovery. In this research, the effect of heavy metals on actinobacteria …
technique for drug discovery. In this research, the effect of heavy metals on actinobacteria …
FLASH irradiation induces lower levels of DNA damage ex vivo, an effect modulated by oxygen tension, dose, and dose rate
Objective: FLASH irradiation reportedly produces less normal tissue toxicity, while
maintaining tumour response. To investigate oxygen's role in the 'FLASH effect', we …
maintaining tumour response. To investigate oxygen's role in the 'FLASH effect', we …
Imidacloprid: Comparative toxicity, DNA damage, ROS production and risk assessment for aquatic non-target organisms
R Nugnes, C Russo, E Orlo, M Lavorgna… - Environmental Pollution, 2023 - Elsevier
Imidacloprid is a neonicotinoid systemic insecticide used worldwide. Despite its hazardous
impact on non-target organisms, few studies have been conducted concerning the potential …
impact on non-target organisms, few studies have been conducted concerning the potential …
[HTML][HTML] Adverse (geno) toxic effects of bisphenol A and its analogues in hepatic 3D cell model
Bisphenol A (BPA) is one of the most widely used and versatile chemical compounds in
polymer additives and epoxy resins for manufacturing a range of products for human …
polymer additives and epoxy resins for manufacturing a range of products for human …